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Amicus Therapeutics
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Overview Fund Activity

265 hedge funds and large institutions have $1.82B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 117 increasing their positions, 79 reducing their positions, and 47 closing their positions.

Holders
265
Holders Change
-16
Holders Change %
-5.69%
% of All Funds
3.56%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
117
Reduced
79
Closed
47
Calls
$2.34M
Puts
$1.56M
Net Calls
+$782K
Net Calls Change
+$2.62M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Assenagon Asset Management
4
Assenagon Asset Management
Luxembourg
$20.2M
5
Qube Research & Technologies (QRT)
5
Qube Research & Technologies (QRT)
United Kingdom
$19.9M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Market Value Shares Shares
Change 		Shares
Change %
State of Wisconsin Investment Board
76
State of Wisconsin Investment Board
Wisconsin
$2.89M 504,128 +97,185 +24%
Swiss National Bank
77
Swiss National Bank
Switzerland
$2.63M 458,700 +24,500 +6%
CM
78
CM Management
Florida
$2.58M 450,000 – –
RhumbLine Advisers
79
RhumbLine Advisers
Massachusetts
$2.49M 434,352 -5,999 -1%
Balyasny Asset Management
80
Balyasny Asset Management
Illinois
$2.42M 421,815 -481,419 -53%
Fidelity Investments
81
Fidelity Investments
Massachusetts
$2.41M 420,209 +33,314 +9%
Rafferty Asset Management
82
Rafferty Asset Management
New York
$2.38M 415,038 +161,274 +64%
Allianz Asset Management
83
Allianz Asset Management
Germany
$2.22M 387,776 +16,367 +4%
AllianceBernstein
84
AllianceBernstein
Tennessee
$2.08M 362,429 – –
Citigroup
85
Citigroup
New York
$2.04M 356,275 -90,164 -20%
SSCM
86
Sovereign's Capital Management
Georgia
$2.04M 355,609 +45,248 +15%
RAM
87
Readystate Asset Management
Illinois
$1.89M 329,917 +329,917 New
DFCM
88
Dark Forest Capital Management
Puerto Rico
$1.79M 311,561 -315,276 -50%
Universal-Beteiligungs- und Servicegesellschaft
89
Universal-Beteiligungs- und Servicegesellschaft
Germany
$1.77M 308,310 +95,565 +45%
Prudential Financial
90
Prudential Financial
New Jersey
$1.57M 273,594 -154,355 -36%
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
91
Healthcare of Ontario Pension Plan (HOOPP) Trust Fund
Ontario, Canada
$1.56M 272,700 +272,700 New
MOACM
92
Mutual of America Capital Management
New York
$1.56M 271,700 +23,091 +9%
Mirae Asset Global ETFs Holdings
93
Mirae Asset Global ETFs Holdings
Hong Kong
$1.52M 265,014 +18,002 +7%
Legal & General Group
94
Legal & General Group
United Kingdom
$1.52M 264,908 +8,375 +3%
OCM
95
Osterweis Capital Management
California
$1.44M 250,935 -573,805 -70%
ACM
96
Aquatic Capital Management
Illinois
$1.43M 249,996 +59,912 +32%
SEI Investments
97
SEI Investments
Pennsylvania
$1.38M 241,289 +55,601 +30%
New York State Common Retirement Fund
98
New York State Common Retirement Fund
New York
$1.37M 238,884 -17,600 -7%
JFG
99
Jefferies Financial Group
New York
$1.28M 223,800 +35,903 +19%
DekaBank Deutsche Girozentrale
100
DekaBank Deutsche Girozentrale
Germany
$1.28M 217,700 – –
2 3
4
5 6