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Amicus Therapeutics
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Overview Fund Activity

265 hedge funds and large institutions have $1.82B invested in Amicus Therapeutics in 2025 Q2 according to their latest regulatory filings, with 35 funds opening new positions, 117 increasing their positions, 79 reducing their positions, and 47 closing their positions.

Holders
265
Holders Change
-16
Holders Change %
-5.69%
% of All Funds
3.56%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
35
Increased
117
Reduced
79
Closed
47
Calls
$2.34M
Puts
$1.56M
Net Calls
+$782K
Net Calls Change
+$2.62M

Top Buyers

1
VPC
1
Vestal Point Capital
New York
$68.2M
2
D.E. Shaw & Co
2
D.E. Shaw & Co
New York
$36.5M
3
Millennium Management
3
Millennium Management
New York
$42.5M
4
Norges Bank
4
Norges Bank
Norway
$18.5M
5
Assenagon Asset Management
5
Assenagon Asset Management
Luxembourg
$20.2M

Top Sellers

1
PA
1
Perceptive Advisors
New York
$42.5M
2
RG
2
Redmile Group
California
$6.81M
3
American Century Companies
3
American Century Companies
Missouri
$0
4
NHAS
4
Novo Holdings A/S
Denmark
$0
5
JPMorgan Chase & Co
5
JPMorgan Chase & Co
New York
$12.7M
Name Market Value Shares Shares
Change 		Shares
Change %
BNP Paribas Financial Markets
51
BNP Paribas Financial Markets
France
$7.16M 1,250,369 +747,461 +149%
RG
52
Redmile Group
California
$6.81M 1,188,998 -8,344,671 -88%
Barclays
53
Barclays
United Kingdom
$6.78M 1,182,735 +546,637 +86%
T. Rowe Price Associates
54
T. Rowe Price Associates
Maryland
$6M 1,046,215 -236,851 -18%
PCM
55
Peregrine Capital Management
Minnesota
$5.8M 1,012,100 +101,592 +11%
SFM
56
Sphera Funds Management
Israel
$5.68M 990,718 +990,718 New
YIH
57
Y-Intercept (HK)
Hong Kong
$5.65M 986,779 +965,328 +4,500%
SAM
58
Silvercrest Asset Management
New York
$5.55M 968,231 +434,520 +81%
6CM
59
683 Capital Management
New York
$5.5M 960,000 +685,000 +249%
Squarepoint
60
Squarepoint
New York
$5.27M 918,885 -621,037 -40%
Two Sigma Advisers
61
Two Sigma Advisers
New York
$5.14M 896,576 -136,700 -13%
TI
62
Trexquant Investment
Connecticut
$4.88M 852,375 +601,703 +240%
SIMG
63
Stephens Investment Management Group
Texas
$4.77M 832,643 +220,173 +36%
Bank of New York Mellon
64
Bank of New York Mellon
New York
$4.6M 803,074 -175,239 -18%
Primecap Management
65
Primecap Management
California
$4.56M 796,100 -123,400 -13%
Capital Fund Management (CFM)
66
Capital Fund Management (CFM)
France
$4.37M 762,698 +450,137 +144%
Two Sigma Investments
67
Two Sigma Investments
New York
$4.2M 732,735 -660,034 -47%
CCIA
68
Campbell & Co Investment Adviser
Maryland
$3.76M 656,111 +656,111 New
EGM
69
Engineers Gate Manager
New York
$3.68M 641,389 +479,038 +295%
VOYA Investment Management
70
VOYA Investment Management
Georgia
$3.59M 625,746 +41,901 +7%
PHP
71
Parkman Healthcare Partners
Connecticut
$3.49M 608,637 +39,685 +7%
Jane Street
72
Jane Street
New York
$3.14M 548,844 -365,718 -40%
Canada Pension Plan Investment Board
73
Canada Pension Plan Investment Board
Ontario, Canada
$2.97M 518,500 +369,800 +249%
PP
74
PDT Partners
New York
$2.9M 506,052 -235,263 -32%
State of Wisconsin Investment Board
75
State of Wisconsin Investment Board
Wisconsin
$2.89M 504,128 +97,185 +24%
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