We are live on ! Find out more
BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

248 hedge funds and large institutions have $3.74B invested in Blueprint Medicines in 2022 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 85 increasing their positions, 91 reducing their positions, and 64 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more call options, than puts

Call options by funds: $11.6M | Put options by funds: $7.29M

0.66% more ownership

Funds ownership: 100.38%101.04% (+0.66%)

7% less repeat investments, than reductions

Existing positions increased: 85 | Existing positions reduced: 91

11% less funds holding

Funds holding: 280248 (-32)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

41% less capital invested

Capital invested by funds: $6.29B → $3.74B (-$2.55B)

47% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 64

Holders
248
Holders Change
-32
Holders Change %
-11.43%
% of All Funds
3.91%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.08%
New
34
Increased
85
Reduced
91
Closed
64
Calls
$11.6M
Puts
$7.29M
Net Calls
+$4.33M
Net Calls Change
+$6.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Millennium Management
51
Millennium Management
New York
$10.4M +$9.39M +130,844 +410%
GIM
52
Granahan Investment Management
Massachusetts
$10M +$7.6M +105,921 +209%
IHAM
53
Integral Health Asset Management
New York
$9.77M +$5.6M +78,000 +104%
EAM
54
EFG Asset Management
Oregon
$8.73M +$1.72M +23,976 +21%
DCM
55
Driehaus Capital Management
Illinois
$8.54M -$13.1M -181,949 -58%
Swiss National Bank
56
Swiss National Bank
Switzerland
$8.44M +$689K +9,600 +8%
PCM
57
Peregrine Capital Management
Minnesota
$8.1M +$230K +3,199 +3%
California Public Employees Retirement System
58
California Public Employees Retirement System
California
$7.92M -$431K -5,998 -5%
VOYA Investment Management
59
VOYA Investment Management
Georgia
$7.44M +$3.19M +44,382 +62%
Comerica Bank
60
Comerica Bank
Texas
$7.37M +$928K +12,927 +13%
EVM
61
Eaton Vance Management
Massachusetts
$6.76M -$11.3M -157,356 -60%
TD Asset Management
62
TD Asset Management
Ontario, Canada
$6.45M -$350K -4,878 -5%
TCM
63
Tekla Capital Management
Massachusetts
$6.21M +$6.98M +97,253 New
Rafferty Asset Management
64
Rafferty Asset Management
New York
$5.98M +$2.81M +39,214 +72%
SAM
65
Sectoral Asset Management
Quebec, Canada
$5.23M +$1.16M +16,100 +24%
B
66
Bailard
California
$5.2M -$1.18M -16,472 -17%
State of Wisconsin Investment Board
67
State of Wisconsin Investment Board
Wisconsin
$5M
Invesco
68
Invesco
Georgia
$4.85M -$1.52M -21,243 -22%
California State Teachers Retirement System (CalSTRS)
69
California State Teachers Retirement System (CalSTRS)
California
$4.65M -$441K -6,145 -8%
Ameriprise
70
Ameriprise
Minnesota
$4.52M +$1.51M +21,029 +42%
Ensign Peak Advisors
71
Ensign Peak Advisors
Utah
$4.51M +$202K +2,810 +4%
Susquehanna International Group
72
Susquehanna International Group
Pennsylvania
$4.5M +$2.56M +35,704 +103%
Renaissance Technologies
73
Renaissance Technologies
New York
$4.37M +$4.91M +68,400 New
Hudson Bay Capital Management
74
Hudson Bay Capital Management
Connecticut
$4.15M +$4.67M +65,000 New
Manulife (Manufacturers Life Insurance)
75
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$4.09M +$2.43M +33,822 +115%

BPMC Hedge Fund Activity: Q1 2022 in Review

248 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q1 2022, worth a combined $3.74B — down 41% from $6.29B a quarter earlier.

Sellers outnumbered buyers: 64 funds closed out of BPMC and 34 opened new positions — a net loss of 30 holders — while 91 trimmed existing stakes and 85 added.

The largest buyer was Fidelity Investments, adding an estimated $214M. The largest seller was TimesSquare Capital Management, cutting an estimated $82.1M.

  • 248 institutional investors held Blueprint Medicines (BPMC) as of Q1 2022, down from 280 in Q4 2021.
  • Funds reported $3.74B of Blueprint Medicines stock for Q1 2022, down 41% quarter-over-quarter.
  • 34 funds opened new Blueprint Medicines positions in Q1 2022 and 64 closed out, a net change of -30 holders.
  • The largest Blueprint Medicines buyer in Q1 2022 was Fidelity Investments, an estimated $214M added.
  • The largest Blueprint Medicines seller in Q1 2022 was TimesSquare Capital Management, an estimated $82.1M sold.

Based on aggregated 13F filings for Q1 2022.