Renaissance Technologies’s Blueprint Medicines BPMC Stock Holding History
Bought
Maintained
Sold
| Quarter | Market Value | Status | Shares |
Change in Stake | Trade Value | Portfolio Weight | Portfolio Position | |
|---|---|---|---|---|---|---|---|---|
|
2025
Q3 | – | Sell |
-674,500
| Closed | -$86.5M | – | 3518 |
|
|
2025
Q2 | $86.5M | Buy |
+674,500
| New | +$70.1M | 0.12% | 187 |
|
|
2025
Q1 | – | Sell |
-126,300
| Closed | -$11M | – | 3480 |
|
|
2024
Q4 | $11M | Sell |
126,300
-48,200
| -28% | -$4.42M | 0.02% | 958 |
|
|
2024
Q3 | $16.1M | Buy |
174,500
+64,100
| +58% | +$6.37M | 0.02% | 790 |
|
|
2024
Q2 | $11.9M | Buy |
110,400
+62,900
| +132% | +$6.3M | 0.02% | 823 |
|
|
2024
Q1 | $4.51M | Buy |
+47,500
| New | +$4.07M | 0.01% | 1486 |
|
|
2023
Q1 | – | Sell |
-85,400
| Closed | -$3.74M | – | 3989 |
|
|
2022
Q4 | $3.74M | Buy |
+85,400
| New | +$4.1M | 0.01% | 1688 |
|
|
2022
Q2 | – | Sell |
-68,400
| Closed | -$4.37M | – | 4230 |
|
|
2022
Q1 | $4.37M | Buy |
+68,400
| New | +$4.91M | 0.01% | 1696 |
|
|
2021
Q3 | – | Sell |
-152,374
| Closed | -$13.4M | – | 3487 |
|
|
2021
Q2 | $13.4M | Sell |
152,374
-47,026
| -24% | -$4.31M | 0.02% | 991 |
|
|
2021
Q1 | $19.4M | Sell |
199,400
-82,500
| -29% | -$8.24M | 0.02% | 790 |
|
|
2020
Q4 | $31.6M | Buy |
281,900
+96,700
| +52% | +$10.2M | 0.03% | 533 |
|
|
2020
Q3 | $17.2M | Buy |
185,200
+125,500
| +210% | +$9.66M | 0.02% | 811 |
|
|
2020
Q2 | $4.66M | Sell |
59,700
-49,500
| -45% | -$3.35M | ﹤0.01% | 1687 |
|
|
2020
Q1 | $6.39M | Buy |
+109,200
| New | +$7.03M | 0.01% | 1423 |
|
|
2018
Q3 | – | Sell |
-245,800
| Closed | -$15.6M | – | 3354 |
|
|
2018
Q2 | $15.6M | Buy |
+245,800
| New | +$19.6M | 0.02% | 1083 |
|
|
2017
Q3 | – | Sell |
-13,000
| Closed | -$659K | – | 3208 |
|
|
2017
Q2 | $659K | Sell |
13,000
-24,400
| -65% | -$1.04M | ﹤0.01% | 2689 |
|
|
2017
Q1 | $1.5M | Buy |
37,400
+26,900
| +256% | +$963K | ﹤0.01% | 2376 |
|
|
2016
Q4 | $295K | Sell |
10,500
-700
| -6% | -$21.1K | ﹤0.01% | 2914 |
|
|
2016
Q3 | $333K | Buy |
+11,200
| New | +$278K | ﹤0.01% | 2931 |
|
Other funds holding BPMC
IA
HNB
Renaissance Technologies's BPMC Position: Q3 2025 in Review
Renaissance Technologies sold out of Blueprint Medicines (BPMC) in Q3 2025, closing a stake of 674,500 shares — an estimated $86.5M sold.
Renaissance Technologies first reported a position in BPMC in Q3 2016 and held it in 18 quarters. The position peaked at $86.5M in Q2 2025. 5 funds tracked by Wall St. Rank hold BPMC as of Q3 2025.
- Renaissance Technologies reported no remaining Blueprint Medicines position as of Q3 2025 after selling out during the quarter.
- Renaissance Technologies sold 674,500 Blueprint Medicines shares in Q3 2025, an estimated $86.5M.
- Renaissance Technologies first reported a position in Blueprint Medicines in Q3 2016 and held it in 18 quarters.
- Renaissance Technologies's Blueprint Medicines position peaked at $86.5M in Q2 2025.
- 5 funds tracked by Wall St. Rank held Blueprint Medicines as of Q3 2025.
Based on Renaissance Technologies's 13F filing for Q3 2025, filed 13 Nov 2025.