|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$680M
|
+$83.7M
|
+704,308
|
+15%
|
|
|
2
|
|
$314M
|
+$12.2M
|
+102,710
|
+4%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$293M
|
+$60.1M
|
+505,802
|
+27%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$168M
|
-$10.7M
|
-90,166
|
-6%
|
|
|
5
|
Baker Bros. Advisors
New York
|
$144M
|
+$46.6M
|
+392,157
|
+51%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$134M
|
-$852K
|
-7,169
|
-0.7%
|
|
|
7
|
Janus Henderson Group
London,
|
$129M
|
-$2.91M
|
-24,501
|
-2%
|
|
|
8
|
VHCP Management II
New York
|
$128M
|
–
|
–
|
–
|
|
|
9
|
RA Capital Management
Boston,
Massachusetts
|
$127M
|
-$17M
|
-142,989
|
-12%
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$111M
|
+$8.91M
|
+75,000
|
+9%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$102M
|
+$25.5M
|
+214,544
|
+35%
|
|
|
12
|
Deerfield Management
New York
|
$93.4M
|
–
|
–
|
–
|
|
|
13
|
Avoro Capital Advisors
New York
|
$83.4M
|
+$9.39M
|
+79,045
|
+13%
|
|
|
14
|
Redmile Group
San Francisco,
California
|
$78.7M
|
+$75.7M
|
+636,900
|
New
|
|
|
15
|
First Trust Advisors
Wheaton,
Illinois
|
$75.7M
|
+$69.6M
|
+585,739
|
+2,163%
|
|
|
16
|
PointState Capital
New York
|
$72.5M
|
+$44.3M
|
+372,780
|
+175%
|
|
|
17
|
Franklin Resources
San Mateo,
California
|
$67.3M
|
+$22.2M
|
+187,155
|
+52%
|
|
|
18
|
AllianceBernstein
Nashville,
Tennessee
|
$65.3M
|
+$7.18M
|
+60,399
|
+13%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$58.2M
|
-$71.9M
|
-605,093
|
-56%
|
|
|
20
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$57.6M
|
+$19.2M
|
+161,882
|
+53%
|
|
|
21
|
Eventide Asset Management
Boston,
Massachusetts
|
$52M
|
–
|
–
|
–
|
|
|
22
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$50.7M
|
-$3.78M
|
-31,838
|
-7%
|
|
|
23
|
BB Biotech
Schaffhausen,
Switzerland
|
$49.8M
|
–
|
–
|
–
|
|
|
24
|
TimesSquare Capital Management
New York
|
$44.8M
|
+$16.9M
|
+142,375
|
+65%
|
|
|
25
|
Eagle Asset Management
St Petersburg,
Florida
|
$42.8M
|
-$943K
|
-7,939
|
-2%
|
|
