|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$387M
|
+$40.8M
|
+544,475
|
+13%
|
|
|
2
|
Deerfield Management
New York
|
$190M
|
+$5.36M
|
+71,429
|
+3%
|
|
|
3
|
|
$189M
|
+$44.5M
|
+592,843
|
+35%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$129M
|
+$28.5M
|
+380,396
|
+32%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$122M
|
+$50.8M
|
+677,235
|
+83%
|
|
|
6
|
RA Capital Management
Boston,
Massachusetts
|
$108M
|
-$23.6M
|
-315,165
|
-19%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$82.2M
|
+$38.3M
|
+510,189
|
+104%
|
|
|
8
|
Citadel Advisors
Miami,
Florida
|
$79.1M
|
+$50M
|
+666,434
|
+225%
|
|
|
9
|
VHCP Management II
New York
|
$77M
|
–
|
–
|
–
|
|
|
10
|
Point72 Asset Management
Stamford,
Connecticut
|
$74.4M
|
+$14.1M
|
+188,153
|
+26%
|
|
|
11
|
Viking Global Investors
Stamford,
Connecticut
|
$73.4M
|
+$38.4M
|
+511,632
|
+134%
|
|
|
12
|
Boxer Capital
San Diego,
California
|
$65.7M
|
-$17.2M
|
-228,763
|
-22%
|
|
|
13
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$63.7M
|
-$16.9M
|
-224,961
|
-22%
|
|
|
14
|
Janus Henderson Group
London,
|
$55.4M
|
+$50.6M
|
+674,765
|
New
|
|
|
15
|
Baker Bros. Advisors
New York
|
$51.4M
|
+$9.37M
|
+125,000
|
+25%
|
|
|
16
|
Millennium Management
New York
|
$50.8M
|
+$18.1M
|
+241,411
|
+64%
|
|
|
17
|
|
$48.2M
|
-$2.72M
|
-36,213
|
-6%
|
|
|
18
|
AllianceBernstein
Nashville,
Tennessee
|
$46.4M
|
+$41.4M
|
+552,546
|
+4,449%
|
|
|
19
|
PointState Capital
New York
|
$44.8M
|
+$22.2M
|
+295,600
|
+119%
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
$35.9M
|
-$35.7M
|
-476,190
|
-52%
|
|
|
21
|
BB Biotech
Schaffhausen,
Switzerland
|
$33.1M
|
+$5.25M
|
+70,000
|
+21%
|
|
|
22
|
Eventide Asset Management
Boston,
Massachusetts
|
$27.9M
|
+$19.4M
|
+258,529
|
+319%
|
|
|
23
|
Bain Capital Public Equity Management
Boston,
Massachusetts
|
$26.2M
|
+$14.9M
|
+198,138
|
+164%
|
|
|
24
|
Marshall Wace North America
New York
|
$24.9M
|
+$20.2M
|
+269,900
|
+813%
|
|
|
25
|
Perceptive Advisors
New York
|
$22.3M
|
-$13.3M
|
-177,320
|
-40%
|
|
