|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$102M
|
+$67.9M
|
+1,788,666
|
+260%
|
|
|
2
|
Deerfield Management
New York
|
$92.2M
|
–
|
–
|
–
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$71.4M
|
+$14.9M
|
+392,892
|
+29%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$57.4M
|
+$5.53M
|
+145,590
|
+12%
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$46.6M
|
+$26.5M
|
+697,060
|
+160%
|
|
|
6
|
VHCP Management II
New York
|
$42.7M
|
–
|
–
|
–
|
|
|
7
|
Vanguard Group
Malvern,
Pennsylvania
|
$36.9M
|
+$23.8M
|
+626,351
|
+233%
|
|
|
8
|
|
$34M
|
+$13.3M
|
+349,613
|
+73%
|
|
|
9
|
Janus Henderson Investors US
Denver,
Colorado
|
$25.2M
|
+$12.7M
|
+333,597
|
+120%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$21.1M
|
-$4.75M
|
-125,000
|
-20%
|
|
|
11
|
Marshall Wace
London,
United Kingdom
|
$17.7M
|
+$16.3M
|
+429,572
|
New
|
|
|
12
|
BlackRock Advisors
Wilmington,
Delaware
|
$17.4M
|
+$5.33M
|
+140,363
|
+50%
|
|
|
13
|
Great Point Partners
Greenwich,
Connecticut
|
$15.7M
|
+$14.5M
|
+381,095
|
New
|
|
|
14
|
BB Biotech
Schaffhausen,
Switzerland
|
$14.5M
|
+$13.4M
|
+352,800
|
New
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$13.6M
|
+$12.5M
|
+329,179
|
New
|
|
|
16
|
Millennium Management
New York
|
$13.5M
|
+$12.4M
|
+326,495
|
New
|
|
|
17
|
Boxer Capital
San Diego,
California
|
$12.4M
|
+$5.97M
|
+157,092
|
+110%
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$9.44M
|
+$7.1M
|
+187,057
|
+446%
|
|
|
19
|
|
$9.26M
|
-$684K
|
-18,000
|
-7%
|
|
|
20
|
|
$8.24M
|
+$1.45M
|
+38,100
|
+24%
|
|
|
21
|
Laurion Capital Management
New York
|
$8.04M
|
+$7.41M
|
+194,980
|
New
|
|
|
22
|
Perceptive Advisors
New York
|
$7.83M
|
+$7.16M
|
+188,485
|
+12,441%
|
|
|
23
|
Jennison Associates
New York
|
$7.55M
|
+$128K
|
+3,362
|
+2%
|
|
|
24
|
BlackRock Group
London,
United Kingdom
|
$7.27M
|
+$2.49M
|
+65,626
|
+59%
|
|
|
25
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$6.04M
|
+$4.59M
|
+120,843
|
+471%
|
|
