|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$531M
|
+$767K
|
+7,646
|
+0.2%
|
|
|
2
|
|
$270M
|
-$9.75M
|
-97,172
|
-4%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$207M
|
+$22.1M
|
+220,676
|
+13%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$160M
|
+$11.4M
|
+113,172
|
+8%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$130M
|
-$6.72M
|
-66,903
|
-5%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$121M
|
-$20.7M
|
-206,288
|
-16%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$119M
|
+$8M
|
+79,743
|
+8%
|
|
|
8
|
Janus Henderson Group
London,
|
$118M
|
+$4.17M
|
+41,558
|
+4%
|
|
|
9
|
VHCP Management II
New York
|
$115M
|
–
|
–
|
–
|
|
|
10
|
Boxer Capital
San Diego,
California
|
$91.3M
|
+$2.51M
|
+25,000
|
+3%
|
|
|
11
|
Baker Bros. Advisors
New York
|
$85.8M
|
–
|
–
|
–
|
|
|
12
|
Deerfield Management
New York
|
$83.6M
|
-$79.5M
|
-791,588
|
-51%
|
|
|
13
|
Point72 Asset Management
Stamford,
Connecticut
|
$67.8M
|
-$3.11M
|
-31,026
|
-5%
|
|
|
14
|
Avoro Capital Advisors
New York
|
$66M
|
+$16M
|
+159,515
|
+37%
|
|
|
15
|
Perceptive Advisors
New York
|
$53.1M
|
-$19.2M
|
-191,040
|
-28%
|
|
|
16
|
Viking Global Investors
Stamford,
Connecticut
|
$52.9M
|
-$11.3M
|
-113,022
|
-19%
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$51.8M
|
-$4.59M
|
-45,766
|
-9%
|
|
|
18
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$48.9M
|
-$15.4M
|
-153,673
|
-26%
|
|
|
19
|
Eventide Asset Management
Boston,
Massachusetts
|
$46.6M
|
+$8.18M
|
+81,471
|
+24%
|
|
|
20
|
BB Biotech
Schaffhausen,
Switzerland
|
$44.6M
|
–
|
–
|
–
|
|
|
21
|
Westfield Capital Management
Boston,
Massachusetts
|
$44.4M
|
-$768K
|
-7,650
|
-2%
|
|
|
22
|
Millennium Management
New York
|
$41.6M
|
+$5.41M
|
+53,891
|
+17%
|
|
|
23
|
Franklin Resources
San Mateo,
California
|
$39.6M
|
-$3.33M
|
-33,195
|
-8%
|
|
|
24
|
Eagle Asset Management
St Petersburg,
Florida
|
$39.3M
|
+$19.6M
|
+195,626
|
+123%
|
|
|
25
|
|
$37.9M
|
+$13.5M
|
+134,809
|
+65%
|
|
