|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$463M
|
+$7.52M
|
+83,383
|
+2%
|
|
|
2
|
|
$246M
|
+$21.5M
|
+237,953
|
+10%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$159M
|
+$6.42M
|
+71,211
|
+5%
|
|
|
4
|
Deerfield Management
New York
|
$150M
|
-$68.6M
|
-760,744
|
-33%
|
|
|
5
|
Adage Capital Partners
Boston,
Massachusetts
|
$129M
|
-$14M
|
-155,147
|
-10%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$126M
|
+$26.9M
|
+298,794
|
+30%
|
|
|
7
|
RA Capital Management
Boston,
Massachusetts
|
$120M
|
-$6.48M
|
-71,865
|
-5%
|
|
|
8
|
VHCP Management II
New York
|
$100M
|
–
|
–
|
–
|
|
|
9
|
Janus Henderson Group
London,
|
$99.4M
|
+$31.8M
|
+352,456
|
+52%
|
|
|
10
|
Citadel Advisors
Miami,
Florida
|
$96.4M
|
+$3.02M
|
+33,445
|
+3%
|
|
|
11
|
Boxer Capital
San Diego,
California
|
$77.4M
|
–
|
–
|
–
|
|
|
12
|
Baker Bros. Advisors
New York
|
$75M
|
+$13.5M
|
+150,000
|
+24%
|
|
|
13
|
Perceptive Advisors
New York
|
$64.9M
|
+$36.1M
|
+400,000
|
+148%
|
|
|
14
|
Point72 Asset Management
Stamford,
Connecticut
|
$62.3M
|
-$23.6M
|
-262,030
|
-29%
|
|
|
15
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$57.6M
|
-$16.2M
|
-179,816
|
-23%
|
|
|
16
|
Viking Global Investors
Stamford,
Connecticut
|
$57.2M
|
-$27.2M
|
-301,898
|
-34%
|
|
|
17
|
AllianceBernstein
Nashville,
Tennessee
|
$49.7M
|
-$4.61M
|
-51,063
|
-9%
|
|
|
18
|
|
$45.2M
|
-$10.8M
|
-119,450
|
-20%
|
|
|
19
|
Avoro Capital Advisors
New York
|
$42.2M
|
+$39.4M
|
+436,702
|
New
|
|
|
20
|
Westfield Capital Management
Boston,
Massachusetts
|
$39.6M
|
+$36.9M
|
+409,000
|
New
|
|
|
21
|
BB Biotech
Schaffhausen,
Switzerland
|
$39M
|
–
|
–
|
–
|
|
|
22
|
Franklin Resources
San Mateo,
California
|
$37.8M
|
-$4.18M
|
-46,327
|
-11%
|
|
|
23
|
Eventide Asset Management
Boston,
Massachusetts
|
$32.8M
|
–
|
–
|
–
|
|
|
24
|
Millennium Management
New York
|
$31.1M
|
-$26.8M
|
-297,075
|
-48%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$29.1M
|
+$4.64M
|
+51,480
|
+21%
|
|
