|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$198M
|
+$89.5M
|
+1,674,424
|
+68%
|
|
|
2
|
Deerfield Management
New York
|
$107M
|
–
|
–
|
–
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$90.2M
|
+$8.47M
|
+158,522
|
+9%
|
|
|
4
|
Franklin Resources
San Mateo,
California
|
$57.1M
|
+$3.5M
|
+65,550
|
+6%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$51.1M
|
+$9.32M
|
+174,452
|
+19%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$50.2M
|
-$18.2M
|
-340,360
|
-24%
|
|
|
7
|
VHCP Management II
New York
|
$49.4M
|
–
|
–
|
–
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$49.1M
|
+$39M
|
+729,007
|
+243%
|
|
|
9
|
Adage Capital Partners
Boston,
Massachusetts
|
$43M
|
+$20.7M
|
+387,075
|
+75%
|
|
|
10
|
|
$40.5M
|
+$1.23M
|
+23,063
|
+3%
|
|
|
11
|
|
$27.5M
|
+$30.8M
|
+576,700
|
New
|
|
|
12
|
Citadel Advisors
Miami,
Florida
|
$26.3M
|
+$11.9M
|
+222,547
|
+68%
|
|
|
13
|
Janus Henderson Investors US
Denver,
Colorado
|
$26.2M
|
-$3.32M
|
-62,219
|
-10%
|
|
|
14
|
BlackRock Fund Advisors
San Francisco,
California
|
$25.8M
|
+$22.3M
|
+417,460
|
+338%
|
|
|
15
|
Point72 Asset Management
Stamford,
Connecticut
|
$25.8M
|
+$28.9M
|
+540,400
|
New
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$25.4M
|
+$24.5M
|
+458,295
|
+619%
|
|
|
17
|
BlackRock Advisors
Wilmington,
Delaware
|
$24M
|
+$4.3M
|
+80,507
|
+19%
|
|
|
18
|
Perceptive Advisors
New York
|
$22.6M
|
+$15.2M
|
+283,531
|
+149%
|
|
|
19
|
Great Point Partners
Greenwich,
Connecticut
|
$19.7M
|
+$1.71M
|
+32,084
|
+8%
|
|
|
20
|
BB Biotech
Schaffhausen,
Switzerland
|
$16.8M
|
–
|
–
|
–
|
|
|
21
|
BlackRock Institutional Trust
San Francisco,
California
|
$15.6M
|
+$5.18M
|
+96,936
|
+42%
|
|
|
22
|
Baker Bros. Advisors
New York
|
$15M
|
+$16.8M
|
+315,300
|
New
|
|
|
23
|
PointState Capital
New York
|
$10.7M
|
+$12M
|
+225,000
|
New
|
|
|
24
|
|
$10.7M
|
–
|
–
|
–
|
|
|
25
|
BlackRock Group
London,
United Kingdom
|
$9.07M
|
+$729K
|
+13,633
|
+8%
|
|
