|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$316M
|
+$589K
|
+9,515
|
+0.2%
|
|
|
2
|
Deerfield Management
New York
|
$170M
|
–
|
–
|
–
|
|
|
3
|
|
$130M
|
+$102M
|
+1,654,248
|
+3,056%
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$124M
|
-$16.4M
|
-265,585
|
-14%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$90.8M
|
+$7.72M
|
+124,750
|
+12%
|
|
|
6
|
VHCP Management II
New York
|
$78.7M
|
–
|
–
|
–
|
|
|
7
|
Boxer Capital
San Diego,
California
|
$78.2M
|
–
|
–
|
–
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$76.1M
|
-$3.19M
|
-51,484
|
-5%
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$69.5M
|
-$17.5M
|
-283,442
|
-24%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$61.7M
|
-$5.45M
|
-88,100
|
-10%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$54.6M
|
+$11M
|
+177,114
|
+33%
|
|
|
12
|
|
$47.4M
|
-$14M
|
-225,713
|
-27%
|
|
|
13
|
|
$43.8M
|
–
|
–
|
–
|
|
|
14
|
Janus Henderson Investors US
Denver,
Colorado
|
$39.7M
|
-$1.71M
|
-27,671
|
-5%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$38M
|
+$11.4M
|
+184,700
|
+59%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$37.2M
|
-$2.63M
|
-42,500
|
-8%
|
|
|
17
|
Perceptive Advisors
New York
|
$34.1M
|
-$1.55M
|
-25,030
|
-5%
|
|
|
18
|
Viking Global Investors
Stamford,
Connecticut
|
$29M
|
+$23.6M
|
+381,626
|
New
|
|
|
19
|
Millennium Management
New York
|
$28.7M
|
+$16.5M
|
+265,841
|
+238%
|
|
|
20
|
BB Biotech
Schaffhausen,
Switzerland
|
$25.3M
|
-$1.24M
|
-20,000
|
-6%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$22.5M
|
-$15.8M
|
-255,384
|
-46%
|
|
|
22
|
PointState Capital
New York
|
$18.9M
|
+$1.49M
|
+24,067
|
+11%
|
|
|
23
|
|
$17.3M
|
+$12M
|
+193,934
|
+570%
|
|
|
24
|
Avoro Capital Advisors
New York
|
$17.1M
|
+$13.9M
|
+225,370
|
New
|
|
|
25
|
|
$16.8M
|
-$272K
|
-4,400
|
-2%
|
|
