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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
QIM
426
Quantitative Investment Management
Virginia
$403K +$403K +1,238 New
FRA
427
Frank Rimerman Advisors
California
$400K +$400K +1,227 New
LNWWM
428
Laird Norton Wetherby Wealth Management
California
$400K +$400K +1,226 New
NW
429
NewEdge Wealth
Pennsylvania
$392K +$392K +902 New
Envestnet Portfolio Solutions
430
Envestnet Portfolio Solutions
Illinois
$380K +$96.8K +297 +34%
MC
431
Mathes Company
New York
$377K +$377K +1,155 New
PCM
432
Peregrine Capital Management
Minnesota
$374K – – –
SCA
433
Snowden Capital Advisors
New York
$370K +$100K +307 +37%
Group One Trading
434
Group One Trading
Illinois
$370K -$1.65M -5,068 -82%
MAS
435
Meeder Advisory Services
Ohio
$367K +$47.9K +147 +15%
CA
436
Clearstead Advisors
Ohio
$366K -$59K -181 -14%
HFM
437
Harvest Fund Management
China
$366K +$366K +1,125 New
OIA
438
OneDigital Investment Advisors
Kansas
$364K -$30.7K -94 -8%
Wolverine Trading
439
Wolverine Trading
Illinois
$362K -$425K -1,316 -54%
TFIPS
440
Towarzystwo Funduszy Inwestycyjnych PZU SA
$359K -$19.6K -60 -5%
ET
441
Entropy Technologies
New York
$359K +$359K +1,100 New
DT
442
Diversified Trust
Tennessee
$358K -$125K -384 -26%
KAS
443
Kestra Advisory Services
Texas
$353K +$41.1K +126 +13%
CBA
444
Coastal Bridge Advisors
Connecticut
$350K -$20.9K -64 -6%
CGPCS
445
Capital Group Private Client Services
California
$349K -$256K -786 -42%
CGH
446
Crossmark Global Holdings
Texas
$340K +$8.48K +26 +3%
NPA
447
Nichols & Pratt Advisers
Massachusetts
$340K – – –
BPA
448
Beacon Pointe Advisors
California
$338K +$55.1K +169 +19%
BJL
449
Brighton Jones LLC
Washington
$336K -$57.7K -177 -15%
BCG
450
Breakwater Capital Group
New Jersey
$335K -$652 -2 -0.2%
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