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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
Capital World Investors
1
Capital World Investors
California
$5.48B +$18.1M +55,384 +0.3%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$5.15B +$162M +496,661 +3%
Vanguard Group
3
Vanguard Group
Pennsylvania
$4.34B +$78.4M +240,534 +2%
BlackRock
4
BlackRock
New York
$3.25B +$137M +420,781 +4%
Capital Research Global Investors
5
Capital Research Global Investors
California
$2.35B +$12M +36,928 +0.5%
RP
6
Regeneron Pharmaceuticals
New York
$1.45B – – –
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$1.4B -$44.6M -136,866 -3%
Dodge & Cox
8
Dodge & Cox
California
$1.04B -$50.4M -154,666 -5%
State Street
9
State Street
Massachusetts
$1.03B -$63.1M -193,478 -6%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$1.03B -$117M -360,162 -10%
Baillie Gifford & Co
11
Baillie Gifford & Co
United Kingdom
$989M -$204M -625,716 -17%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$780M +$24.7M +75,936 +3%
OAG
13
Orbis Allan Gray
Bermuda
$692M +$159M +486,489 +30%
Wellington Management Group
14
Wellington Management Group
Massachusetts
$677M -$175M -535,234 -20%
JPMorgan Chase & Co
15
JPMorgan Chase & Co
New York
$672M -$51.2M -156,864 -7%
Norges Bank
16
Norges Bank
Norway
$663M +$663M +2,032,680 New
American Century Companies
17
American Century Companies
Missouri
$585M +$10.9M +33,411 +2%
Invesco
18
Invesco
Georgia
$438M +$140M +427,902 +47%
Bank of America
19
Bank of America
North Carolina
$410M +$62.9M +192,755 +18%
Winslow Capital Management
20
Winslow Capital Management
Minnesota
$384M -$3.18M -9,739 -0.8%
UBS AM
21
UBS AM
Illinois
$313M +$72.5M +222,225 +30%
Legal & General Group
22
Legal & General Group
United Kingdom
$285M -$2.72M -8,340 -0.9%
Northern Trust
23
Northern Trust
Illinois
$271M -$10.8M -33,243 -4%
NL
24
Nuveen LLC
North Carolina
$253M -$35.3M -108,405 -12%
Morgan Stanley
25
Morgan Stanley
New York
$251M +$42.1M +129,203 +20%
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