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Alnylam Pharmaceuticals

433 hedge funds and large institutions have $18.6B invested in Alnylam Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 76 funds opening new positions, 157 increasing their positions, 131 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

90% more first-time investments, than exits

New positions opened: 76 | Existing positions closed: 40

32% more call options, than puts

Call options by funds: $249M | Put options by funds: $189M

20% more repeat investments, than reductions

Existing positions increased: 157 | Existing positions reduced: 131

7% more funds holding

Funds holding: 403433 (+30)

0.24% less ownership

Funds ownership: 93.95%93.7% (-0.24%)

11% less capital invested

Capital invested by funds: $21B → $18.6B (-$2.35B)

22% less funds holding in top 10

Funds holding in top 10: 97 (-2)

Holders
433
Holders Change
+30
Holders Change %
+7.44%
% of All Funds
6.66%
Holding in Top 10
7
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-22.22%
% of All Funds
0.11%
New
76
Increased
157
Reduced
131
Closed
40
Calls
$249M
Puts
$189M
Net Calls
+$59.8M
Net Calls Change
-$76.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$3.04B +$21M +113,092 +0.6%
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.81B +$16.4M +88,189 +0.8%
Baillie Gifford & Co
3
Baillie Gifford & Co
United Kingdom
$1.8B +$37.4M +200,967 +2%
BlackRock
4
BlackRock
New York
$1.3B -$232M -1,249,570 -14%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$1.16B -$97.9M -526,642 -7%
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$1.11B +$123M +661,133 +11%
Dodge & Cox
7
Dodge & Cox
California
$921M +$11M +58,968 +1%
JP Morgan Chase
8
JP Morgan Chase
New York
$504M +$97.8M +526,426 +22%
State Street
9
State Street
Massachusetts
$483M +$9.21M +49,564 +2%
RI
10
RTW Investments
New York
$335M +$54.4M +292,517 +17%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$255M +$9.53M +51,272 +4%
BG
12
Bellevue Group
Switzerland
$226M -$13.6M -73,278 -5%
Massachusetts Financial Services
13
Massachusetts Financial Services
Massachusetts
$224M -$8.01M -43,076 -3%
Norges Bank
14
Norges Bank
Norway
$215M +$51M +274,303 +28%
FCM
15
Farallon Capital Management
California
$202M +$69.8M +375,727 +46%
ACA
16
Avoro Capital Advisors
New York
$182M +$41.8M +225,000 +26%
Morgan Stanley
17
Morgan Stanley
New York
$181M -$152M -815,190 -43%
American Century Companies
18
American Century Companies
Missouri
$170M -$12.8M -68,897 -6%
CC
19
Casdin Capital
New York
$170M
Loomis, Sayles & Company
20
Loomis, Sayles & Company
Massachusetts
$169M +$5.27M +28,330 +3%
Federated Hermes
21
Federated Hermes
Pennsylvania
$168M +$6.2M +33,360 +3%
Invesco
22
Invesco
Georgia
$151M -$30.5M -164,082 -16%
GGHC
23
Gilder Gagnon Howe & Co
New York
$142M -$15.6M -84,116 -9%
Northern Trust
24
Northern Trust
Illinois
$130M -$1.8M -9,708 -1%
Holocene Advisors
25
Holocene Advisors
New York
$123M +$11.4M +61,509 +9%

ALNY Hedge Fund Activity: Q4 2021 in Review

433 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q4 2021, worth a combined $18.6B — down 11% from $21B a quarter earlier.

Buyers outnumbered sellers: 76 funds opened new ALNY positions and 40 closed out — a net gain of 36 holders — while 157 added to existing stakes and 131 trimmed.

The largest buyer was T. Rowe Price Associates, adding an estimated $123M. The largest seller was BlackRock, cutting an estimated $232M.

  • 433 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q4 2021, up from 403 in Q3 2021.
  • Funds reported $18.6B of Alnylam Pharmaceuticals stock for Q4 2021, down 11% quarter-over-quarter.
  • 76 funds opened new Alnylam Pharmaceuticals positions in Q4 2021 and 40 closed out, a net change of +36 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q4 2021 was T. Rowe Price Associates, an estimated $123M added.
  • The largest Alnylam Pharmaceuticals seller in Q4 2021 was BlackRock, an estimated $232M sold.

Based on aggregated 13F filings for Q4 2021.