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Alnylam Pharmaceuticals

626 hedge funds and large institutions have $34.8B invested in Alnylam Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 106 funds opening new positions, 237 increasing their positions, 205 reducing their positions, and 67 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more funds holding in top 10

Funds holding in top 10: 410 (+6)

58% more first-time investments, than exits

New positions opened: 106 | Existing positions closed: 67

16% more capital invested

Capital invested by funds: $30.1B → $34.8B (+$4.78B)

16% more repeat investments, than reductions

Existing positions increased: 237 | Existing positions reduced: 205

15% more call options, than puts

Call options by funds: $274M | Put options by funds: $238M

6% more funds holding

Funds holding: 593626 (+33)

0.45% more ownership

Funds ownership: 99.08%99.53% (+0.45%)

Holders
626
Holders Change
+33
Holders Change %
+5.56%
% of All Funds
8.39%
Holding in Top 10
10
Holding in Top 10 Change
+6
Holding in Top 10 Change %
+150%
% of All Funds
0.13%
New
106
Increased
237
Reduced
205
Closed
67
Calls
$274M
Puts
$238M
Net Calls
+$35.4M
Net Calls Change
+$6.38M
Name Holding Trade Value Shares
Change
Change in
Stake
Capital World Investors
1
Capital World Investors
California
$4.52B +$38.3M +149,098 +0.9%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$4.13B +$469M +1,823,957 +14%
Vanguard Group
3
Vanguard Group
Pennsylvania
$3.53B +$83.1M +323,206 +3%
BlackRock
4
BlackRock
New York
$2.58B -$83.7M -325,875 -3%
Capital Research Global Investors
5
Capital Research Global Investors
California
$1.93B +$47.9M +186,215 +3%
RP
6
Regeneron Pharmaceuticals
New York
$1.2B
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$1.19B +$8.66M +33,696 +0.8%
Baillie Gifford & Co
8
Baillie Gifford & Co
United Kingdom
$988M -$98.3M -382,652 -9%
T. Rowe Price Associates
9
T. Rowe Price Associates
Maryland
$946M +$47.7M +185,783 +6%
State Street
10
State Street
Massachusetts
$909M -$14.5M -56,294 -2%
Dodge & Cox
11
Dodge & Cox
California
$905M -$48.4M -188,500 -5%
Wellington Management Group
12
Wellington Management Group
Massachusetts
$705M -$408M -1,585,637 -38%
Geode Capital Management
13
Geode Capital Management
Massachusetts
$626M +$29.8M +116,034 +5%
JP Morgan Chase
14
JP Morgan Chase
New York
$599M -$8.02M -31,188 -1%
Norges Bank
15
Norges Bank
Norway
$577M -$82.3M -320,058 -13%
American Century Companies
16
American Century Companies
Missouri
$475M +$40.2M +156,411 +10%
OAG
17
Orbis Allan Gray
Bermuda
$441M +$41.7M +162,121 +11%
Winslow Capital Management
18
Winslow Capital Management
Minnesota
$321M +$42.8M +166,611 +16%
Bank of America
19
Bank of America
North Carolina
$287M +$166M +646,021 +154%
Invesco
20
Invesco
Georgia
$247M +$91.3M +355,302 +64%
Legal & General Group
21
Legal & General Group
United Kingdom
$238M +$13.4M +52,194 +6%
Northern Trust
22
Northern Trust
Illinois
$234M -$3.56M -13,840 -2%
AQR Capital Management
23
AQR Capital Management
Connecticut
$217M +$3.85M +14,988 +2%
BG
24
Bellevue Group
Switzerland
$207M -$545K -2,121 -0.3%
UBS AM
25
UBS AM
Illinois
$199M +$6.56M +25,513 +4%

ALNY Hedge Fund Activity: Q1 2025 in Review

626 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q1 2025, worth a combined $34.8B — up 16% from $30.1B a quarter earlier.

Buyers outnumbered sellers: 106 funds opened new ALNY positions and 67 closed out — a net gain of 39 holders — while 237 added to existing stakes and 205 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $469M. The largest seller was Wellington Management Group, cutting an estimated $408M.

  • 626 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q1 2025, up from 593 in Q4 2024.
  • Funds reported $34.8B of Alnylam Pharmaceuticals stock for Q1 2025, up 16% quarter-over-quarter.
  • 106 funds opened new Alnylam Pharmaceuticals positions in Q1 2025 and 67 closed out, a net change of +39 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q1 2025 was Fidelity Investments, an estimated $469M added.
  • The largest Alnylam Pharmaceuticals seller in Q1 2025 was Wellington Management Group, an estimated $408M sold.

Based on aggregated 13F filings for Q1 2025.