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Alnylam Pharmaceuticals

784 hedge funds and large institutions have $40.1B invested in Alnylam Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 87 funds opening new positions, 319 increasing their positions, 280 reducing their positions, and 80 closing their positions.

New
Increased
Maintained
Reduced
Closed

113% more call options, than puts

Call options by funds: $453M | Put options by funds: $213M

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

14% more repeat investments, than reductions

Existing positions increased: 319 | Existing positions reduced: 280

9% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 80

0.64% more ownership

Funds ownership: 99.08%99.72% (+0.64%)

1% less funds holding

Funds holding: 791784 (-7)

8% less capital invested

Capital invested by funds: $43.4B → $40.1B (-$3.32B)

Holders
784
Holders Change
-7
Holders Change %
-0.88%
% of All Funds
9.47%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.06%
New
87
Increased
319
Reduced
280
Closed
80
Calls
$453M
Puts
$213M
Net Calls
+$240M
Net Calls Change
-$5M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$4.52B +$134M +444,796 +3%
Capital World Investors
2
Capital World Investors
California
$3.35B +$103M +342,498 +3%
BlackRock
3
BlackRock
New York
$3.28B +$140M +462,767 +4%
Capital Research Global Investors
4
Capital Research Global Investors
California
$2.94B +$84.3M +279,518 +3%
Vanguard Portfolio Management
5
Vanguard Portfolio Management
Pennsylvania
$1.97B +$14.2M +47,110 +0.7%
Vanguard Capital Management
6
Vanguard Capital Management
Pennsylvania
$1.82B +$25M +82,772 +1%
T. Rowe Price Investment Management
7
T. Rowe Price Investment Management
Maryland
$1.7B +$135M +448,849 +9%
Invesco
8
Invesco
Georgia
$1.13B -$96.8M -320,802 -8%
State Street
9
State Street
Massachusetts
$1.07B +$70.3M +232,991 +7%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$791M -$7.4M -24,545 -0.9%
JP Morgan Chase
11
JP Morgan Chase
New York
$785M -$1.1B -3,648,235 -58%
Baillie Gifford & Co
12
Baillie Gifford & Co
United Kingdom
$734M -$16.3M -53,977 -2%
Norges Bank
13
Norges Bank
Norway
$684M +$685M +2,271,813 New
Wellington Management Group
14
Wellington Management Group
Massachusetts
$635M +$52.6M +174,482 +9%
OAG
15
Orbis Allan Gray
Bermuda
$598M +$197M +652,582 +49%
Dodge & Cox
16
Dodge & Cox
California
$589M +$7.88M +26,140 +1%
Two Sigma Investments
17
Two Sigma Investments
New York
$565M -$35.2M -116,640 -6%
American Century Companies
18
American Century Companies
Missouri
$558M +$15.6M +51,593 +3%
ClearBridge Investments
19
ClearBridge Investments
New York
$379M -$29.1M -96,553 -7%
T. Rowe Price Associates
20
T. Rowe Price Associates
Maryland
$346M -$85.5M -283,547 -20%
D.E. Shaw & Co
21
D.E. Shaw & Co
New York
$332M +$13.6M +45,047 +4%
Morgan Stanley
22
Morgan Stanley
New York
$311M +$8.89M +29,469 +3%
Bank of America
23
Bank of America
North Carolina
$299M +$8.31M +27,564 +3%
Legal & General Group
24
Legal & General Group
United Kingdom
$278M -$3.11M -10,320 -1%
Manulife (Manufacturers Life Insurance)
25
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$269M +$69.8M +231,430 +35%

ALNY Hedge Fund Activity: Q2 2026 in Review

784 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Alnylam Pharmaceuticals (ALNY) for Q2 2026, worth a combined $40.1B — down 7.7% from $43.4B a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new ALNY positions and 80 closed out — a net gain of 7 holders — while 319 added to existing stakes and 280 trimmed.

The largest buyer was Deep Track Capital, opening a new position worth an estimated $249M. The largest seller was JP Morgan Chase, cutting an estimated $1.1B.

  • 784 institutional investors held Alnylam Pharmaceuticals (ALNY) as of Q2 2026, down from 791 in Q1 2026.
  • Funds reported $40.1B of Alnylam Pharmaceuticals stock for Q2 2026, down 7.7% quarter-over-quarter.
  • 87 funds opened new Alnylam Pharmaceuticals positions in Q2 2026 and 80 closed out, a net change of +7 holders.
  • The largest Alnylam Pharmaceuticals buyer in Q2 2026 was Deep Track Capital, an estimated $249M added.
  • The largest Alnylam Pharmaceuticals seller in Q2 2026 was JP Morgan Chase, an estimated $1.1B sold.

Based on aggregated 13F filings for Q2 2026.