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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
WP
451
Westmount Partners
California
$326K – – –
GCM
452
Greenland Capital Management
New York
$326K – – –
LS
453
Livforsakringsbolaget Skandia
Sweden
$325K – – –
JAM
454
Jupiter Asset Management
United Kingdom
$318K -$4.45M -13,636 -93%
NL
455
NWAM LLC
Washington
$310K +$1.7K +5 +0.6%
SFC
456
SYM Financial Corp
Indiana
$308K -$22.8K -70 -7%
FIM
457
Freedom Investment Management
Connecticut
$305K -$30.7K -94 -9%
HWA
458
HCR Wealth Advisors
California
$301K – – –
SWP
459
Sagespring Wealth Partners
Tennessee
$299K +$299K +916 New
HH
460
Hilltop Holdings
Texas
$299K +$299K +916 New
National Bank of Canada
461
National Bank of Canada
Quebec, Canada
$294K +$78.3K +240 +36%
NRD
462
Nebula Research & Development
New York
$293K +$293K +900 New
HI
463
Humankind Investments
New York
$292K +$292K +896 New
PCP
464
Proficio Capital Partners
Massachusetts
$288K +$24.1K +74 +9%
PAG
465
Poinciana Advisors Group
Florida
$284K +$6.2K +19 +2%
HWM
466
HB Wealth Management
Georgia
$284K +$32K +98 +13%
HCM
467
Howard Capital Management
Georgia
$271K +$271K +830 New
CD
468
Chapin Davis
Maryland
$269K – – –
WFI
469
West Family Investments
California
$268K +$268K +822 New
PAS
470
Point72 Asia (Singapore)
Singapore
$267K -$4.62M -14,188 -95%
PA
471
Parallel Advisors
California
$266K -$14.7K -45 -5%
FPAS
472
Focus Partners Advisor Solutions
Missouri
$263K -$622K -1,914 -70%
IC
473
Iconiq Capital
California
$263K +$263K +806 New
MF
474
Meridian Financial
Massachusetts
$261K – – –
EI
475
Ellevest Inc
New York
$258K +$6.2K +19 +2%
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19
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