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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
EL
476
Essex LLC
Illinois
$257K – – –
CCC
477
Compass Capital Corp
Massachusetts
$254K – – –
AA
478
Alta Advisers
United Kingdom
$247K – – –
SFC
479
Strategic Financial Concepts
Texas
$245K -$652 -2 -0.3%
GS
480
GTS Securities
New York
$244K +$244K +747 New
AG
481
Ascent Group
Virginia
$243K -$978 -3 -0.4%
FTUS
482
Flow Traders U.S.
New York
$241K +$241K +740 New
PWP
483
Perfromance Wealth Partners
Illinois
$240K +$240K +735 New
GI
484
GAMMA Investing
California
$237K +$35.9K +110 +18%
EWA
485
EP Wealth Advisors
California
$233K -$92.9K -285 -29%
FCP
486
Fidelis Capital Partners
Florida
$229K +$229K +536 New
NA
487
NewEdge Advisors
Louisiana
$229K +$229K +703 +70,300%
AF
488
Allworth Financial
California
$225K +$23.8K +73 +12%
SIG
489
Stonegate Investment Group
Alabama
$223K +$223K +684 New
SQA
490
Simon Quick Advisors
New Jersey
$222K +$222K +682 New
FT
491
Fiduciary Trust
Massachusetts
$219K +$219K +673 New
AWM
492
Ariadne Wealth Management
California
$219K +$219K +506 New
AFG
493
Atomi Financial Group
New York
$218K +$218K +667 New
FMLI
494
Fukoku Mutual Life Insurance
Japan
$215K -$83.2K -255 -28%
ZBNA
495
Zions Bancorporation, National Association
Utah
$211K – – –
SI
496
Stephens Inc
Arkansas
$207K +$207K +635 New
CFP
497
Cascade Financial Partners
California
$204K +$204K +627 New
SFS
498
Sowell Financial Services
Arkansas
$201K +$201K +616 New
FDW
499
Fourth Dimension Wealth
Ohio
$192K +$27.7K +85 +17%
SAM
500
Smartleaf Asset Management
Massachusetts
$192K -$97.2K -301 -34%
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