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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 62 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+29
Holders Change %
+4.7%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
62
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
VIA
401
Virtus Investment Advisers
Connecticut
$476K -$2.61K -8 -0.5%
SBF
402
Sara-Bay Financial
Florida
$473K +$147K +450 +45%
AAS
403
Avantax Advisory Services
Texas
$472K +$472K +1,446 New
EMCIP
404
Ewing Morris & Co Investment Partners
Ontario, Canada
$470K +$470K +1,440 New
FB
405
Fulton Bank
Pennsylvania
$463K +$15K +46 +3%
BPC
406
Banque Pictet & Cie
Switzerland
$454K -$30K -92 -6%
Cambridge Investment Research Advisors
407
Cambridge Investment Research Advisors
Iowa
$451K +$194K +595 +75%
SFA
408
Souders Financial Advisors
Ohio
$443K -$142K -434 -24%
SPIA
409
Steward Partners Investment Advisory
New York
$442K +$96.2K +295 +28%
VCM
410
Voleon Capital Management
California
$442K -$3.44M -10,558 -89%
WBC
411
Westpac Banking Corp
Australia
$442K -$1.21M -3,718 -73%
O
412
Ossiam
France
$442K +$6.2K +19 +1%
VT
413
Vise Technologies
New York
$435K +$435K +1,334 New
OAM
414
Oppenheimer Asset Management
New York
$433K +$433K +1,328 New
AAIS
415
ABN AMRO Investment Solutions
$427K – – –
NSAM
416
North Star Asset Management
Wisconsin
$426K – – –
BTI
417
Blue Trust Inc
Georgia
$422K +$44K +135 +12%
BIAS
418
Beacon Investment Advisory Services
New Jersey
$421K -$130K -398 -24%
PMFA
419
Plante Moran Financial Advisors
Michigan
$419K – – –
ALAM
420
Asahi Life Asset Management
Japan
$417K -$52.2K -160 -11%
FRM
421
Fox Run Management
Connecticut
$412K +$412K +1,263 New
TAA
422
TB Alternative Assets
Cayman Islands
$411K -$2.58M -7,909 -86%
CWM
423
Crowley Wealth Management
Delaware
$408K – – –
CI
424
Cigna Investments
Connecticut
$406K -$17K -52 -4%
BS
425
Banco Santander
Spain
$406K +$406K +1,245 New
15 16
17
18 19