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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
KeyBank National Association
351
KeyBank National Association
Ohio
$899K -$12.1K -37 -1%
SFP
352
Shepherd Financial Partners
Massachusetts
$892K – – –
GT
353
Greenleaf Trust
Michigan
$890K -$6.52K -20 -0.7%
Bank of Nova Scotia
354
Bank of Nova Scotia
Ontario, Canada
$874K -$596K -1,827 -41%
AAM
355
Azzad Asset Management
Virginia
$864K +$864K +2,651 New
PCA
356
Pallas Capital Advisors
Massachusetts
$838K -$1.33M -4,065 -61%
Mercer Global Advisors
357
Mercer Global Advisors
Colorado
$836K -$211K -647 -20%
OAM
358
Oxford Asset Management
United Kingdom
$805K +$805K +2,468 New
Squarepoint
359
Squarepoint
New York
$798K -$1.25M -3,822 -61%
Osaic Holdings
360
Osaic Holdings
Arizona
$798K +$316K +1,067 +66%
Kovitz Investment Group Partners
361
Kovitz Investment Group Partners
Illinois
$766K +$326 +1 +0%
NPT
362
Nixon Peabody Trust
Massachusetts
$762K +$19.6K +60 +3%
CIP
363
Convergence Investment Partners
Florida
$737K +$737K +2,259 New
UM
364
UniSuper Management
Australia
$717K -$97.8K -300 -12%
EFG
365
Everhart Financial Group
Ohio
$715K +$132K +406 +23%
SI
366
Sava Infond
Slovenia
$711K +$32.6K +100 +5%
BWMG
367
Bannerman Wealth Management Group
Texas
$706K -$184K -565 -21%
EI
368
Ethic Inc
New York
$703K +$42.9K +133 +7%
QCM
369
QRG Capital Management
Illinois
$697K +$61K +187 +10%
SLI
370
Sumitomo Life Insurance
Japan
$691K +$691K +2,118 New
NYLIM
371
New York Life Investment Management
New York
$686K -$36.2K -111 -5%
PAS
372
Park Avenue Securities
New York
$680K +$680K +2,085 New
ACS
373
Archford Capital Strategies
Illinois
$658K -$652 -2 -0.1%
SNBOSD
374
Security National Bank of So Dak
Iowa
$652K – – –
LAM
375
LECAP Asset Management
United Kingdom
$647K +$90K +276 +16%
13 14
15
16 17