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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
EA
376
Emerald Advisers
Pennsylvania
$633K +$145K +445 +30%
S
377
SignatureFD
Georgia
$622K +$49.2K +151 +9%
GA
378
GraniteShares Advisors
New York
$619K -$68.8K -211 -10%
MFG
379
Merit Financial Group
Georgia
$616K -$1.12M -3,424 -64%
QC
380
Quadrature Capital
United Kingdom
$615K -$5.42M -16,624 -90%
SFI
381
Siemens Fonds Invest
Germany
$601K +$121K +372 +25%
VAS
382
Vestmark Advisory Solutions
Massachusetts
$567K +$567K +1,740 New
WPC
383
Wedmont Private Capital
Pennsylvania
$565K +$54.2K +169 +11%
OC
384
Oppenheimer & Co
New York
$560K – – –
PS
385
Principal Securities
Iowa
$559K +$172K +527 +44%
FSA
386
Fort Sheridan Advisors
Illinois
$555K – – –
VSQM
387
V-Square Quantitative Management
Illinois
$552K +$431K +1,321 +356%
WSFS
388
Wilmington Savings Fund Society
Delaware
$550K +$192K +588 +54%
KCM
389
Kennedy Capital Management
Missouri
$544K +$41.4K +127 +8%
BP
390
Ballentine Partners
Massachusetts
$527K -$2.61K -8 -0.5%
SBFM
391
S-Bank Fund Management
Finland
$526K -$47.6K -146 -8%
CCM
392
Coldstream Capital Management
Washington
$522K +$171K +523 +48%
UCFA
393
United Capital Financial Advisors
Texas
$514K +$14K +43 +3%
YCM
394
Yousif Capital Management
Michigan
$511K -$34.6K -106 -6%
FFM
395
Forum Financial Management
Illinois
$507K +$42.1K +129 +9%
EC
396
EntryPoint Capital
New York
$505K -$265K -814 -34%
LWCFA
397
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$500K – – –
QCM
398
Qsemble Capital Management
New York
$499K +$109K +334 +28%
P
399
&Partners
Tennessee
$498K +$228K +702 +85%
HNWAG
400
High Net Worth Advisory Group
Florida
$489K – – –
14 15
16
17 18