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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
$196M
2
Holocene Advisors
Holocene Advisors
New York
$195M
3
ClearBridge Investments
ClearBridge Investments
New York
$182M
4
Macquarie Group
Macquarie Group
Australia
$196M
5
Fidelity Investments
Fidelity Investments
Massachusetts
$5.15B

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
$61.3M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
$989M
3
Wellington Management Group
Wellington Management Group
Massachusetts
$677M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
$1.03B
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
I
301
InceptionR
California
$1.49M +$1.06M +3,238 +242%
AAM
302
Advisors Asset Management
Colorado
$1.48M -$426K -1,306 -22%
CB
303
Commerce Bank
Missouri
$1.48M -$6.85K -21 -0.5%
OAC
304
OMERS Administration Corp
Ontario, Canada
$1.47M – – –
IIM
305
INTECH Investment Management
Florida
$1.44M -$486K -1,490 -25%
CL
306
Choreo LLC
Illinois
$1.44M +$72.1K +221 +5%
BCI
307
Brinker Capital Investments
Pennsylvania
$1.41M +$147K +452 +12%
CT
308
Clearstead Trust
Maine
$1.4M +$93.9K +288 +7%
AI
309
Atria Investments
North Carolina
$1.39M +$23.5K +72 +2%
ProShare Advisors
310
ProShare Advisors
Maryland
$1.38M -$521K -1,599 -27%
BM
311
Brandywine Managers
Delaware
$1.38M -$42.4K -130 -3%
A
312
AustralianSuper
Australia
$1.38M – – –
CI Investments Inc
313
CI Investments Inc
Ontario, Canada
$1.34M +$618K +1,894 +85%
PP
314
Prudential plc
United Kingdom
$1.34M +$673K +2,065 +101%
PIM
315
Plato Investment Management
Australia
$1.34M -$177K -546 -12%
Truist Financial
316
Truist Financial
North Carolina
$1.31M +$125K +383 +11%
HCM
317
Howland Capital Management
Massachusetts
$1.3M – – –
GC
318
Gilbert & Cook
Iowa
$1.3M +$29.3K +90 +2%
VFA
319
Values First Advisors
Tennessee
$1.29M -$1.36M -4,166 -51%
VA
320
Vident Advisory
Georgia
$1.28M +$410K +1,258 +47%
SFA
321
Sequoia Financial Advisors
Ohio
$1.28M +$170K +522 +15%
SC
322
Savant Capital
Illinois
$1.23M -$4.18M -12,825 -77%
EFM
323
E Fund Management
China
$1.17M -$2.97M -9,114 -72%
WG
324
Winton Group
United Kingdom
$1.15M +$1.15M +3,533 New
CAPTRUST Financial Advisors
325
CAPTRUST Financial Advisors
North Carolina
$1.14M -$938K -2,875 -45%
11 12
13
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