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Alnylam Pharmaceuticals

785 hedge funds and large institutions have $42.5B invested in Alnylam Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 102 funds opening new positions, 320 increasing their positions, 257 reducing their positions, and 153 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

18% less capital invested

Capital invested by funds: $51.7B → $42.5B (-$9.26B)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

33% less first-time investments, than exits

New positions opened: 102 | Existing positions closed: 153

Holders
785
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$450M
Puts
$205M
Net Calls
Net Calls Change

Top Buyers

1 +$1.17B
2 +$916M
3 +$546M
4
Two Sigma Investments
Two Sigma Investments
New York
+$468M
5
ClearBridge Investments
ClearBridge Investments
New York
+$258M

Top Sellers

1 -$1.87B
2 -$450M
3 -$448M
4
Invesco
Invesco
Georgia
-$297M
5
1832 Asset Management
1832 Asset Management
Ontario, Canada
-$175M
Name Holding Trade Value Shares
Change
Change in
Stake
Commonwealth Equity Services
276
Commonwealth Equity Services
Massachusetts
$3.5M
MFAM
277
Motley Fool Asset Management
Virginia
$3.47M
SAM
278
Silvercrest Asset Management
New York
$3.45M
PAM
279
Panagora Asset Management
Massachusetts
$3.42M
GIBU
280
Gulf International Bank (UK)
United Kingdom
$3.37M
MAM
281
Martingale Asset Management
Massachusetts
$3.35M
RBI
282
Raiffeisen Bank International
Austria
$3.29M
AB
283
Amalgamated Bank
New York
$3.29M
AI
284
Atria Investments
North Carolina
$3.27M
HFM
285
Harvest Fund Management
China
$3.26M
PEAK6
286
PEAK6
Illinois
$3.21M
OSAM
287
O'Shaughnessy Asset Management
Connecticut
$3.19M
TRCT
288
Tower Research Capital (TRC)
New York
$3.19M
VAS
289
Vestmark Advisory Solutions
Massachusetts
$3.17M
Fifth Third Bancorp
290
Fifth Third Bancorp
Ohio
$3.17M
CB
291
Commerce Bank
Missouri
$3.14M
William Blair & Company
292
William Blair & Company
Illinois
$3.12M
Nisa Investment Advisors
293
Nisa Investment Advisors
Missouri
$3.1M
Janney Montgomery Scott
294
Janney Montgomery Scott
Pennsylvania
$3.09M
TFA
295
Transamerica Financial Advisors
Florida
$3.08M
NW
296
NewEdge Wealth
Pennsylvania
$3.04M
MOACM
297
Mutual of America Capital Management
New York
$2.96M
Blackstone Inc
298
Blackstone Inc
New York
$2.9M
LSERS
299
Louisiana State Employees Retirement System
Louisiana
$2.88M
Mercer Global Advisors
300
Mercer Global Advisors
Colorado
$2.84M