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Alnylam Pharmaceuticals
ALNY

Overview Fund Activity

646 hedge funds and large institutions have $43B invested in Alnylam Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 97 funds opening new positions, 257 increasing their positions, 214 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
646
Holders Change
+28
Holders Change %
+4.53%
% of All Funds
8.66%
Holding in Top 10
9
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-10%
% of All Funds
0.12%
New
97
Increased
257
Reduced
214
Closed
63
Calls
$188M
Puts
$203M
Net Calls
-$15.5M
Net Calls Change
-$50.8M

Top Buyers

1
Citadel Advisors
Citadel Advisors
Florida
+$195M
2
Holocene Advisors
Holocene Advisors
New York
+$195M
3
ClearBridge Investments
ClearBridge Investments
New York
+$179M
4
Macquarie Group
Macquarie Group
Australia
+$172M
5
Fidelity Investments
Fidelity Investments
Massachusetts
+$162M

Top Sellers

1
AQR Capital Management
AQR Capital Management
Connecticut
-$208M
2
Baillie Gifford & Co
Baillie Gifford & Co
United Kingdom
-$204M
3
Wellington Management Group
Wellington Management Group
Massachusetts
-$175M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$117M
5
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$89.2M
Name Holding Trade Value Shares
Change 		Shares
Change %
TAF
226
Tredje AP-fonden
Sweden
$3.98M -$1.21M -3,705 -23%
SCM
227
Sterling Capital Management
North Carolina
$3.94M -$329K -1,008 -8%
Wealthfront Advisers
228
Wealthfront Advisers
California
$3.94M +$1.1M +3,363 +39%
ZIM
229
Zacks Investment Management
Illinois
$3.89M -$3.37M -10,331 -46%
EAMA
230
EFG Asset Management (Americas)
Florida
$3.79M -$573K -1,757 -13%
RAM
231
Readystate Asset Management
Illinois
$3.78M +$3.78M +11,601 New
AssetMark Inc
232
AssetMark Inc
California
$3.76M +$294K +902 +8%
Mirae Asset Global ETFs Holdings
233
Mirae Asset Global ETFs Holdings
Hong Kong
$3.76M -$780K -2,395 -17%
Nordea Investment Management
234
Nordea Investment Management
Sweden
$3.64M +$342K +1,060 +10%
CFB
235
Cullen/Frost Bankers
Texas
$3.52M +$25.4K +78 +0.7%
CFM
236
Catalyst Funds Management
Australia
$3.51M -$2.75M -8,430 -44%
GC
237
Guggenheim Capital
Illinois
$3.47M -$560K -1,718 -14%
William Blair & Company
238
William Blair & Company
Illinois
$3.45M -$158K -486 -4%
SAM
239
Silvercrest Asset Management
New York
$3.34M +$140K +430 +4%
Cerity Partners
240
Cerity Partners
New York
$3.3M -$1.48M -4,529 -31%
Natixis Advisors
241
Natixis Advisors
Massachusetts
$3.3M +$3.3M +10,109 New
TCM
242
Traynor Capital Management
Pennsylvania
$3.29M +$120K +372 +4%
SCI
243
S&CO Inc
Massachusetts
$3.28M – – –
Commonwealth Equity Services
244
Commonwealth Equity Services
Massachusetts
$3.24M +$474K +1,455 +17%
Cetera Investment Advisers
245
Cetera Investment Advisers
Illinois
$3.22M +$610K +1,871 +23%
PAMP
246
Polar Asset Management Partners
Ontario, Canada
$3.13M +$3.13M +9,600 New
ERSOT
247
Employees Retirement System of Texas
Texas
$3.09M +$3.09M +9,474 New
AB
248
Amalgamated Bank
New York
$3.09M +$201K +615 +7%
Mackenzie Financial
249
Mackenzie Financial
Ontario, Canada
$2.96M -$134K -410 -4%
DJSG
250
D.J. St. Germain
Massachusetts
$2.93M +$2.93M +8,994 New
8 9
10
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