Walleye Capital
UPB

Walleye Capital’s Upstream Bio Inc UPB Stock Holding History

Walleye Capital’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$3.45M Buy
+498,490
New +$4.18M 0.01% 1071
2025
Q2 		– Sell
-10,000
Closed -$61.2K – 5148
2025
Q1 		$61.2K Hold
10,000
– – ﹤0.01% 3787
2024
Q4 		$164K Buy
+10,000
New +$223K ﹤0.01% 3881

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Norges Bank
Norges Bank Oslo, Norway $1T AUM
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $732M AUM 275.56% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $345M AUM 134.64% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return

Walleye Capital's UPB Position: Q2 2026 in Review

Walleye Capital opened a new position in Upstream Bio Inc (UPB) in Q2 2026: 498,490 shares worth $3.45M. The stake represents 0.01% of the portfolio and ranks #1071 among its holdings. This is a return to the name: Walleye Capital previously reported a position in UPB as recently as Q1 2025.

Walleye Capital first reported a position in UPB in Q4 2024 and has held it in 3 quarters since. 148 funds tracked by Wall St. Rank hold UPB as of Q2 2026.

  • Walleye Capital held 498,490 shares of Upstream Bio Inc worth $3.45M as of Q2 2026.
  • Upstream Bio Inc was a new Walleye Capital position in Q2 2026.
  • Upstream Bio Inc made up 0.01% of Walleye Capital's portfolio in Q2 2026, its #1071 holding.
  • Walleye Capital first reported a position in Upstream Bio Inc in Q4 2024 and has held it in 3 quarters since.
  • 148 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q2 2026.

Based on Walleye Capital's 13F filing for Q2 2026, filed 3 Aug 2026.