Two Sigma Securities’s Ionis Pharmaceuticals IONS Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-9,649	Closed	-$763K	–	1905
2025 Q4	$763K	Buy	+9,649	New	+$727K	0.1%	251
2024 Q4	–	Sell	-8,940	Closed	-$358K	–	2391
2024 Q3	$358K	Sell	8,940 -71,258	-89%	-$3.32M	0.01%	1589
2024 Q2	$3.82M	Buy	80,198 +69,076	+621%	+$2.83M	0.05%	437
2024 Q1	$482K	Sell	11,122 -4,282	-28%	-$204K	﹤0.01%	1610
2023 Q4	$779K	Buy	15,404 +10,060	+188%	+$482K	0.01%	1207
2023 Q3	$242K	Buy	+5,344	New	+$220K	﹤0.01%	2133
2022 Q4	–	Sell	-8,670	Closed	-$383K	–	2903
2022 Q3	$383K	Buy	8,670 +2,097	+32%	+$88.4K	0.01%	1335
2022 Q2	$243K	Buy	+6,573	New	+$248K	0.01%	1485
2020 Q1	–	Sell	-6,895	Closed	-$417K	–	1817
2019 Q4	$417K	Buy	+6,895	New	+$411K	﹤0.01%	1562
2018 Q3	–	Sell	-5,113	Closed	-$240K	–	2777
2018 Q2	$213K	Sell	5,113 -2,781	-35%	-$123K	﹤0.01%	2318
2018 Q1	$348K	Buy	7,894 +2,849	+56%	+$145K	﹤0.01%	1907
2017 Q4	$254K	Buy	+5,045	New	+$277K	0.01%	1118
2017 Q3	–	Sell	-11,550	Closed	-$588K	–	1060
2017 Q2	$588K	Buy	+11,550	New	+$538K	0.11%	173