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Two Sigma Securities’s Ionis Pharmaceuticals IONS Stock Holding History

Two Sigma Securities’s Portfolio IONS Stock Details IONS Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2024
Q4 		– Sell
-5,200
Closed -$208K – 2392
2024
Q3 		$208K Buy
5,200
+500
+11% +$23.3K ﹤0.01% 2115
2024
Q2 		$224K Sell
4,700
-1,100
-19% -$45.1K ﹤0.01% 2259
2024
Q1 		$251K Buy
5,800
+1,100
+23% +$52.4K ﹤0.01% 2123
2023
Q4 		$238K Sell
4,700
-2,400
-34% -$115K ﹤0.01% 2226
2023
Q3 		$322K Sell
7,100
-300
-4% -$12.4K ﹤0.01% 1892
2023
Q2 		$304K Buy
+7,400
New +$284K ﹤0.01% 1860
2022
Q4 		– Sell
-5,300
Closed -$234K – 2904
2022
Q3 		$234K Buy
+5,300
New +$223K 0.01% 1804
2022
Q2 		– Sell
-6,900
Closed -$256K – 2526
2022
Q1 		$256K Buy
+6,900
New +$226K 0.01% 1540
2020
Q1 		– Sell
-4,800
Closed -$290K – 1818
2019
Q4 		$290K Buy
+4,800
New +$286K ﹤0.01% 1812
2018
Q4 		– Sell
-14,500
Closed -$748K – 2469
2018
Q3 		$748K Buy
14,500
+5,700
+65% +$268K ﹤0.01% 1173
2018
Q2 		$367K Sell
8,800
-300
-3% -$13.3K ﹤0.01% 1939
2018
Q1 		$401K Buy
+9,100
New +$462K ﹤0.01% 1814

Other funds holding IONS

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
T. Rowe Price Investment Management
T. Rowe Price Investment Management Baltimore, Maryland $153B AUM 38.14% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Two Sigma Securities's IONS Position: Q1 2026 in Review

Two Sigma Securities sold out of Ionis Pharmaceuticals (IONS) in Q1 2026, closing a stake of 9,649 shares — an estimated $763K sold.

Two Sigma Securities first reported a position in IONS in Q2 2017 and held it in 13 quarters. The position peaked at $3.82M in Q2 2024. 496 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

  • Two Sigma Securities reported no remaining Ionis Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
  • Two Sigma Securities sold 9,649 Ionis Pharmaceuticals shares in Q1 2026, an estimated $763K.
  • Two Sigma Securities first reported a position in Ionis Pharmaceuticals in Q2 2017 and held it in 13 quarters.
  • Two Sigma Securities's Ionis Pharmaceuticals position peaked at $3.82M in Q2 2024.
  • 496 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on Two Sigma Securities's 13F filing for Q1 2026, filed 15 May 2026.