Two Sigma Securities’s Ionis Pharmaceuticals IONS Stock Holding History

Two Sigma Securities’s Portfolio IONS Stock Details IONS Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2024 Q2	–	Sell	-5,500	Closed	-$238K	–	3318
2024 Q1	$238K	Buy	5,500 +800	+17%	+$38.1K	﹤0.01%	2174
2023 Q4	$238K	Sell	4,700 -4,000	-46%	-$192K	﹤0.01%	2225
2023 Q3	$395K	Sell	8,700 -1,400	-14%	-$57.8K	﹤0.01%	1712
2023 Q2	$414K	Buy	+10,100	New	+$388K	0.01%	1579
2022 Q4	–	Sell	-8,200	Closed	-$363K	–	2902
2022 Q3	$363K	Buy	+8,200	New	+$346K	0.01%	1382
2022 Q2	–	Sell	-7,000	Closed	-$259K	–	2525
2022 Q1	$259K	Buy	+7,000	New	+$229K	0.01%	1528
2020 Q1	–	Sell	-3,500	Closed	-$211K	–	1816
2019 Q4	$211K	Sell	3,500 -2,800	-44%	-$167K	﹤0.01%	2059
2019 Q3	$377K	Buy	+6,300	New	+$411K	﹤0.01%	1393
2019 Q1	–	Sell	-6,000	Closed	-$324K	–	2130
2018 Q4	$324K	Sell	6,000 -40,500	-87%	-$2.07M	﹤0.01%	1301
2018 Q3	$2.4M	Sell	46,500 -11,300	-20%	-$531K	0.02%	624
2018 Q2	$2.41M	Buy	57,800 +28,100	+95%	+$1.25M	0.01%	810
2018 Q1	$1.31M	Buy	+29,700	New	+$1.51M	0.01%	1104

Other funds holding IONS

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return

T. Rowe Price Investment Management Baltimore, Maryland $153B AUM 38.14% 1-Year Est. Return

Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Two Sigma Securities's IONS Position: Q1 2026 in Review

Two Sigma Securities sold out of Ionis Pharmaceuticals (IONS) in Q1 2026, closing a stake of 9,649 shares — an estimated $763K sold.

Two Sigma Securities first reported a position in IONS in Q2 2017 and held it in 13 quarters. The position peaked at $3.82M in Q2 2024. 496 funds tracked by Wall St. Rank hold IONS as of Q1 2026.

Two Sigma Securities reported no remaining Ionis Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
Two Sigma Securities sold 9,649 Ionis Pharmaceuticals shares in Q1 2026, an estimated $763K.
Two Sigma Securities first reported a position in Ionis Pharmaceuticals in Q2 2017 and held it in 13 quarters.
Two Sigma Securities's Ionis Pharmaceuticals position peaked at $3.82M in Q2 2024.
496 funds tracked by Wall St. Rank held Ionis Pharmaceuticals as of Q1 2026.

Based on Two Sigma Securities's 13F filing for Q1 2026, filed 15 May 2026.