State Street
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State Street’s Amylyx Pharmaceuticals AMLX Stock Holding History

State Street’s Portfolio AMLX Stock Details AMLX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$46.8M Buy
2,603,337
+240,176
+10% +$3.71M ﹤0.01% 1883
2026
Q1 		$32.8M Buy
2,363,161
+293,277
+14% +$4.13M ﹤0.01% 1963
2025
Q4 		$25M Buy
2,069,884
+448,624
+28% +$6.09M ﹤0.01% 2137
2025
Q3 		$22M Buy
1,621,260
+612,351
+61% +$5.76M ﹤0.01% 2187
2025
Q2 		$6.47M Buy
1,008,909
+747,126
+285% +$3.63M ﹤0.01% 2824
2025
Q1 		$927K Buy
261,783
+43,400
+20% +$154K ﹤0.01% 3444
2024
Q4 		$825K Buy
218,383
+63,475
+41% +$299K ﹤0.01% 3522
2024
Q3 		$502K Hold
154,908
– – ﹤0.01% 3595
2024
Q2 		$294K Sell
154,908
-1,905,134
-92% -$3.69M ﹤0.01% 3706
2024
Q1 		$5.85M Buy
2,060,042
+618,640
+43% +$8.09M ﹤0.01% 2862
2023
Q4 		$21.2M Buy
1,441,402
+201,649
+16% +$3.09M ﹤0.01% 2178
2023
Q3 		$22.7M Buy
1,239,753
+82,054
+7% +$1.74M ﹤0.01% 2102
2023
Q2 		$25M Buy
1,157,699
+91,461
+9% +$2.47M ﹤0.01% 2107
2023
Q1 		$31.3M Sell
1,066,238
-9,374
-0.9% -$326K ﹤0.01% 1943
2022
Q4 		$39.7M Buy
1,075,612
+248,544
+30% +$8.82M ﹤0.01% 1788
2022
Q3 		$23.3M Buy
827,068
+630,603
+321% +$15.7M ﹤0.01% 2109
2022
Q2 		$3.78M Buy
196,465
+97,253
+98% +$1.15M ﹤0.01% 3236
2022
Q1 		$1.27M Buy
+99,212
New +$2.24M ﹤0.01% 3730

Other funds holding AMLX

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $4.16B AUM 983.43% 1-Year Est. Return
CC
Commodore Capital New York $1.68B AUM 375.52% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
SVCM
Saturn V Capital Management Austin, Texas $697M AUM 628.57% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return

State Street's AMLX Position: Q2 2026 in Review

State Street increased its Amylyx Pharmaceuticals (AMLX) stake by 10% in Q2 2026, buying an estimated $3.71M and bringing the position to 2,603,337 shares worth $46.8M. The position accounts for ﹤0.01% of the portfolio, ranked #1883.

State Street first reported a position in AMLX in Q1 2022 and has held it in 18 quarters since. 207 funds tracked by Wall St. Rank hold AMLX as of Q2 2026.

  • State Street held 2,603,337 shares of Amylyx Pharmaceuticals worth $46.8M as of Q2 2026.
  • State Street bought 240,176 Amylyx Pharmaceuticals shares in Q2 2026, an estimated $3.71M.
  • Amylyx Pharmaceuticals made up ﹤0.01% of State Street's portfolio in Q2 2026, its #1883 holding.
  • State Street first reported a position in Amylyx Pharmaceuticals in Q1 2022 and has held it in 18 quarters since.
  • 207 funds tracked by Wall St. Rank held Amylyx Pharmaceuticals as of Q2 2026.

Based on State Street's 13F filing for Q2 2026, filed 7 Aug 2026.