Janus Henderson Group
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Janus Henderson Group’s Amylyx Pharmaceuticals AMLX Stock Holding History

Janus Henderson Group’s Portfolio AMLX Stock Details AMLX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$69.3M Buy
4,986,073
+520,201
+12% +$7.32M 0.03% 345
2025
Q4 		$54M Buy
4,465,872
+1,929,639
+76% +$26.2M 0.02% 399
2025
Q3 		$34.5M Buy
+2,536,233
New +$23.9M 0.02% 488
2024
Q2 		– Sell
-14,717
Closed -$41.9K – 2526
2024
Q1 		$41.9K Sell
14,717
-36
-0.2% -$471 ﹤0.01% 2526
2023
Q4 		$217K Sell
14,753
-1
-0% -$15 ﹤0.01% 2405
2023
Q3 		$270K Buy
14,754
+1
+0% +$21 ﹤0.01% 2243
2023
Q2 		$318K Buy
+14,753
New +$398K ﹤0.01% 2220

Other funds holding AMLX

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
SVCM
Saturn V Capital Management Austin, Texas $552M AUM 551.78% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
FLAM
First Light Asset Management Edina, Minnesota $1.12B AUM 114.45% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Janus Henderson Group's AMLX Position: Q1 2026 in Review

Janus Henderson Group increased its Amylyx Pharmaceuticals (AMLX) stake by 12% in Q1 2026, buying an estimated $7.32M and bringing the position to 4,986,073 shares worth $69.3M. The position accounts for 0.03% of the portfolio, ranked #345.

Janus Henderson Group first reported a position in AMLX in Q2 2023 and has held it in 7 quarters since. 171 funds tracked by Wall St. Rank hold AMLX as of Q1 2026.

  • Janus Henderson Group held 4,986,073 shares of Amylyx Pharmaceuticals worth $69.3M as of Q1 2026.
  • Janus Henderson Group bought 520,201 Amylyx Pharmaceuticals shares in Q1 2026, an estimated $7.32M.
  • Amylyx Pharmaceuticals made up 0.03% of Janus Henderson Group's portfolio in Q1 2026, its #345 holding.
  • Janus Henderson Group first reported a position in Amylyx Pharmaceuticals in Q2 2023 and has held it in 7 quarters since.
  • 171 funds tracked by Wall St. Rank held Amylyx Pharmaceuticals as of Q1 2026.

Based on Janus Henderson Group's 13F filing for Q1 2026, filed 15 May 2026.