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Sphera Funds Management’s Arrowhead Research ARWR Stock Holding History

Sphera Funds Management’s Portfolio ARWR Stock Details ARWR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-12,496
Closed -$431K – 101
2025
Q3 		$431K Sell
12,496
-190,500
-94% -$4.19M 0.09% 107
2025
Q2 		$3.21M Sell
202,996
-74,554
-27% -$1.07M 0.75% 49
2025
Q1 		$3.54M Buy
277,550
+80,000
+40% +$1.45M 0.81% 37
2024
Q4 		$3.71M Buy
+197,550
New +$4.07M 0.67% 57
2024
Q3 		– Sell
-48,175
Closed -$1.25M – 120
2024
Q2 		$1.25M Buy
+48,175
New +$1.18M 0.17% 100
2024
Q1 		– Sell
-144,899
Closed -$4.43M – 107
2023
Q4 		$4.43M Buy
+144,899
New +$3.85M 0.71% 54
2016
Q4 		– Sell
-100,000
Closed -$735K – 108
2016
Q3 		$735K Buy
+100,000
New +$648K 0.12% 97
2016
Q1 		– Sell
-486,000
Closed -$2.99M – 93
2015
Q4 		$2.99M Sell
486,000
-54,000
-10% -$306K 0.44% 57
2015
Q3 		$3.11M Buy
540,000
+65,000
+14% +$409K 0.4% 55
2015
Q2 		$3.4M Buy
+475,000
New +$3.26M 0.33% 73
2015
Q1 		– Sell
-400,000
Closed -$2.95M – 147
2014
Q4 		$2.95M Buy
+400,000
New +$2.72M 0.5% 64
2014
Q3 		– Sell
-100,000
Closed -$1.43M – 129
2014
Q2 		$1.43M Buy
+100,000
New +$1.31M 0.35% 67
2014
Q1 		– Sell
-20,000
Closed -$217K – 115
2013
Q4 		$217K Buy
+20,000
New +$160K 0.06% 94

Other funds holding ARWR

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return
SPC
Slate Path Capital New York $7.22B AUM 110.75% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Arrowstreet Capital
Arrowstreet Capital Boston, Massachusetts $225B AUM 49.49% 1-Year Est. Return
FAM
Fred Alger Management New York $30B AUM 76.99% 1-Year Est. Return

Sphera Funds Management's ARWR Position: Q4 2025 in Review

Sphera Funds Management sold out of Arrowhead Research (ARWR) in Q4 2025, closing a stake of 12,496 shares — an estimated $431K sold.

Sphera Funds Management first reported a position in ARWR in Q4 2013 and held it in 13 quarters. The position peaked at $4.43M in Q4 2023. 401 funds tracked by Wall St. Rank hold ARWR as of Q4 2025.

  • Sphera Funds Management reported no remaining Arrowhead Research position as of Q4 2025 after selling out during the quarter.
  • Sphera Funds Management sold 12,496 Arrowhead Research shares in Q4 2025, an estimated $431K.
  • Sphera Funds Management first reported a position in Arrowhead Research in Q4 2013 and held it in 13 quarters.
  • Sphera Funds Management's Arrowhead Research position peaked at $4.43M in Q4 2023.
  • 401 funds tracked by Wall St. Rank held Arrowhead Research as of Q4 2025.

Based on Sphera Funds Management's 13F filing for Q4 2025, filed 17 Feb 2026.