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Siren LLC’s Lexicon Pharmaceuticals LXRX Stock Holding History

Siren LLC’s Portfolio LXRX Stock Details LXRX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$69.1M Buy
44,303,518
+5,384,615
+14% +$7.83M 1.92% 14
2025
Q4 		$44.8M Hold
38,918,903
– – 1.34% 25
2025
Q3 		$52.5M Hold
38,918,903
– – 2.06% 14
2025
Q2 		$36.8M Hold
38,918,903
– – 1.9% 15
2025
Q1 		$17.9M Hold
38,918,903
– – 1.01% 26
2024
Q4 		$28.8M Hold
38,918,903
– – 1.27% 24
2024
Q3 		$61.1M Buy
+38,918,903
New +$69.3M 3.05% 9

Other funds holding LXRX

AG
Artal Group Luxembourg $1.01B AUM 29.84% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
SC
Sessa Capital New York $5.51B AUM 47.23% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Jane Street
Jane Street New York $777B AUM 61.18% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return

Siren LLC's LXRX Position: Q1 2026 in Review

Siren LLC increased its Lexicon Pharmaceuticals (LXRX) stake by 14% in Q1 2026, buying an estimated $7.83M and bringing the position to 44,303,518 shares worth $69.1M. The position accounts for 1.92% of the portfolio, ranked #14.

Siren LLC first reported a position in LXRX in Q3 2024 and has held it in 7 quarters since. 136 funds tracked by Wall St. Rank hold LXRX as of Q1 2026.

  • Siren LLC held 44,303,518 shares of Lexicon Pharmaceuticals worth $69.1M as of Q1 2026.
  • Siren LLC bought 5,384,615 Lexicon Pharmaceuticals shares in Q1 2026, an estimated $7.83M.
  • Lexicon Pharmaceuticals made up 1.92% of Siren LLC's portfolio in Q1 2026, its #14 holding.
  • Siren LLC first reported a position in Lexicon Pharmaceuticals in Q3 2024 and has held it in 7 quarters since.
  • 136 funds tracked by Wall St. Rank held Lexicon Pharmaceuticals as of Q1 2026.

Based on Siren LLC's 13F filing for Q1 2026, filed 14 May 2026.