LXRX icon

Lexicon Pharmaceuticals

1.07 USD
-0.02
1.83%
At close Jul 29, 4:00 PM EDT
Pre-market
1.08
+0.01
0.93%
1 day
-1.83%
5 days
-11.57%
1 month
13.14%
3 months
59.99%
6 months
29.65%
Year to date
37.69%
1 year
-53.48%
5 years
-38.51%
10 years
-87.37%
 

About: Lexicon Pharmaceuticals Inc is a biopharmaceutical company. It is engaged in the discovery, development, and commercialization of pharmaceutical products for the treatment of human diseases. Some of its drug candidates are LX9211, an orally-delivered small molecule drug candidate, also developing LX9851, an orally-delivered small molecule drug candidate, as a treatment for obesity and associated cardiometabolic.

Employees: 103

0
Funds holding %
of 7,323 funds
Analysts bullish %

Fund manager confidence

Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)

588% more call options, than puts

Call options by funds: $358K | Put options by funds: $52K

10% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 29

6% more repeat investments, than reductions

Existing positions increased: 34 | Existing positions reduced: 32

1% more funds holding

Funds holding: 126 [Q4 2024] → 127 (+1) [Q1 2025]

0% more funds holding in top 10

Funds holding in top 10: 1 [Q4 2024] → 1 (+0) [Q1 2025]

8.81% less ownership

Funds ownership: 82.34% [Q4 2024] → 73.53% (-8.81%) [Q1 2025]

44% less capital invested

Capital invested by funds: $220M [Q4 2024] → $122M (-$97.6M) [Q1 2025]

Research analyst outlook

1 Wall Street Analyst provided 1 year price targets over the past 3 months

Low target
$4
274%
upside
Avg. target
$4
274%
upside
High target
$4
274%
upside

1 analyst rating

positive
100%
neutral
0%
negative
0%
HC Wainwright & Co.
Joseph Pantginis
274%upside
$4
Buy
Reiterated
24 Jun 2025

Financial journalist opinion

Neutral
GlobeNewsWire
1 week ago
Lexicon Pharmaceuticals to Report Second Quarter 2025 Financial Results on August 6, 2025
THE WOODLANDS, Texas, July 23, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will release its second quarter 2025 financial results on Wednesday, August 6, 2025, prior to market open. Management will conduct a conference call and live webcast at 8:30 a.m. ET (7:30 a.m. CT) that day to discuss the financial results and to provide a business update.
Lexicon Pharmaceuticals to Report Second Quarter 2025 Financial Results on August 6, 2025
Neutral
GlobeNewsWire
1 week ago
Lexicon to Present Patient-reported Data on Diabetic Peripheral Neuropathic Pain (DPNP) at the 7th Annual Meeting of the American Society of Pain and Neuroscience (ASPN 2025)
Patient insights informed the development of pilavapadin, Lexicon's investigational, novel, non-opioid treatment for people suffering from DPNP Patient insights informed the development of pilavapadin, Lexicon's investigational, novel, non-opioid treatment for people suffering from DPNP
Lexicon to Present Patient-reported Data on Diabetic Peripheral Neuropathic Pain (DPNP) at the 7th Annual Meeting of the American Society of Pain and Neuroscience (ASPN 2025)
Neutral
GlobeNewsWire
1 month ago
Data Demonstrating Sotagliflozin Reduces the Risk of Clinically Important Hypoglycemic Events in Adults with Type 1 Diabetes When Added to Insulin Presented at the 85th Scientific Sessions of the American Diabetes Association (ADA)
Oral presentation highlighted the post-hoc analysis during the “Interventions to Prevent Hypoglycemia: Bench to Bedside” session Treatment with sotagliflozin resulted in no increased risk and a reduction in hypoglycemia events, particularly in patients with blood glucose ≤55 mg/dL THE WOODLANDS, Texas, June 23, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) announced that a post-hoc analysis of clinical study data showing a reduction in hypoglycemic events when sotagliflozin was added to optimized insulin therapy for people with type 1 diabetes (T1D) was presented yesterday during the 85th Scientific Sessions of the American Diabetes Association (ADA) in Chicago, Illinois. The ADA emphasizes that hypoglycemia remains an important patient management issue in T1D.
Data Demonstrating Sotagliflozin Reduces the Risk of Clinically Important Hypoglycemic Events in Adults with Type 1 Diabetes When Added to Insulin Presented at the 85th Scientific Sessions of the American Diabetes Association (ADA)
Neutral
GlobeNewsWire
1 month ago
Lexicon to Present Data at the 85th Scientific Sessions of the American Diabetes Association (ADA)
THE WOODLANDS, Texas, June 18, 2025 (GLOBE NEWSWIRE) --   Lexicon Pharmaceuticals, Inc.  (Nasdaq: LXRX) today announced that data from a study evaluating the impact of sotagliflozin on hypoglycemia in people with type 1 diabetes will be delivered as an oral presentation on Sunday, June 22, during the 85th Scientific Sessions of the American Diabetes Association (ADA). At the meeting, the company will also present topline data from its PROGRESS Phase 2b study evaluating pilavapadin (LX9211) in adults with diabetic peripheral neuropathic pain.
Lexicon to Present Data at the 85th Scientific Sessions of the American Diabetes Association (ADA)
Neutral
GlobeNewsWire
2 months ago
Lexicon Pharmaceuticals to Present at the 2025 Jefferies Global Healthcare Conference
THE WOODLANDS, Texas, May 29, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 2025 Jefferies Global Healthcare Conference, taking place in New York City on Thursday, June 5 at 12:50 p.m. ET. The live event and a replay of the presentation can be accessed via the Events page of the Company's website at https://investors.lexpharma.com/.
Lexicon Pharmaceuticals to Present at the 2025 Jefferies Global Healthcare Conference
Neutral
GlobeNewsWire
2 months ago
SONATA-HCM Study Design Presented at Heart Failure 2025, the Annual Congress of the Heart Failure Association of the European Society of Cardiology
Lexicon is evaluating the safety and efficacy of sotagliflozin in patients with both obstructive and  non-obstructive hypertrophic cardiomyopathy (HCM) Pivotal Phase 3 clinical trial is actively enrolling patients in 20 countries, with all sites expected to be operational by Q3 2025 THE WOODLANDS, Texas, May 19, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced details of its “ SO tagliflozi N in Patients with Symptom AT ic obstructive A nd non-obstructive H ypertrophic C ardio M yopathy (SONATA-HCM)” study were presented on Saturday, May 17. The study design was disclosed in Belgrade, Serbia at one of the premier international heart failure meetings: Heart Failure 2025, the Annual Congress of the Heart Failure Association of the European Society of Cardiology.
SONATA-HCM Study Design Presented at Heart Failure 2025, the Annual Congress of the Heart Failure Association of the European Society of Cardiology
Neutral
Seeking Alpha
2 months ago
Lexicon Pharmaceuticals, Inc. (LXRX) Q1 2025 Earnings Call Transcript
Lexicon Pharmaceuticals, Inc. (NASDAQ:LXRX ) Q1 2025 Earnings Conference Call May 13, 2025 5:00 PM ET Company Participants Lisa DeFrancesco - Senior Vice President, Investor Relations and Corporate Strategy Mike Exton - Chief Executive Officer and Director Scott Coiante - Senior Vice President and Chief Financial Officer Craig Granowitz - Senior Vice President and Chief Medical Officer Conference Call Participants Andrew Tsai - Jefferies Roanna Ruiz - Leerink Partners Yasmeen Rahimi - Piper Sandler Yigal Nochomovitz - Citigroup Lander Gorrono - H.C. Wainwright Operator Welcome to the Lexicon Pharmaceuticals First Quarter 2025 Financial Results Conference Call.
Lexicon Pharmaceuticals, Inc. (LXRX) Q1 2025 Earnings Call Transcript
Negative
Zacks Investment Research
2 months ago
Lexicon Pharmaceuticals (LXRX) Reports Q1 Loss, Lags Revenue Estimates
Lexicon Pharmaceuticals (LXRX) came out with a quarterly loss of $0.07 per share versus the Zacks Consensus Estimate of a loss of $0.10. This compares to loss of $0.20 per share a year ago.
Lexicon Pharmaceuticals (LXRX) Reports Q1 Loss, Lags Revenue Estimates
Neutral
GlobeNewsWire
2 months ago
Lexicon Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides Business Updates
Company had a strong start to 2025, emerging as an R&D-focused organization Exclusive license agreement with Novo Nordisk for LX9851 executed; IND-enabling studies on track for completion in 2025 Phase 2b PROGRESS study confirmed 10 mg pilavapadin as appropriate dose for advancement into Phase 3 development for diabetic peripheral neuropathic pain Conference call and webcast at 5:00 pm ET THE WOODLANDS, Texas, May 13, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), today reported financial results for the three months ended March 31, 2025, and provided an update on key corporate milestones and accomplishments. “We began 2025 delivering on three of our goals for this year, including most recently an exclusive licensing agreement with Novo Nordisk for LX9851 in obesity and related disorders,” said Mike Exton, Ph.D.
Lexicon Pharmaceuticals Reports First Quarter 2025 Financial Results and Provides Business Updates
Neutral
GlobeNewsWire
2 months ago
Lexicon Pharmaceuticals to Present at the 3rd Annual H.C. Wainwright BioConnect Investor Conference
THE WOODLANDS, Texas, May 06, 2025 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that Company management will participate in a fireside chat at the 3rd Annual H.C. Wainwright BioConnect Investor Conference, taking place at the Nasdaq World Headquarters in New York City, on Tuesday, May 20, at 9:30 a.m. ET.
Lexicon Pharmaceuticals to Present at the 3rd Annual H.C. Wainwright BioConnect Investor Conference
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