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Lexicon Pharmaceuticals

136 hedge funds and large institutions have $505M invested in Lexicon Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 31 funds opening new positions, 41 increasing their positions, 26 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,280% more call options, than puts

Call options by funds: $3.34M | Put options by funds: $242K

107% more first-time investments, than exits

New positions opened: 31 | Existing positions closed: 15

68% more capital invested

Capital invested by funds: $299M → $505M (+$205M)

58% more repeat investments, than reductions

Existing positions increased: 41 | Existing positions reduced: 26

9% more funds holding

Funds holding: 125136 (+11)

4.66% more ownership

Funds ownership: 71.66%76.33% (+4.7%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
136
Holders Change
+11
Holders Change %
+8.8%
% of All Funds
1.67%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
31
Increased
41
Reduced
26
Closed
15
Calls
$3.34M
Puts
$242K
Net Calls
+$3.1M
Net Calls Change
+$2.25M
Name Holding Trade Value Shares
Change
Change in
Stake
AG
1
Artal Group
Luxembourg
$241M +$27M +18,553,846 +14%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$70.3M +$10.5M +7,222,131 +19%
SL
3
Siren LLC
Connecticut
$69.1M +$7.83M +5,384,615 +14%
SC
4
Sessa Capital
New York
$27.9M +$21.7M +14,912,961 +497%
VCM
5
Vanguard Capital Management
Pennsylvania
$14.8M +$13.8M +9,519,167 New
Point72 Asset Management
6
Point72 Asset Management
Connecticut
$12.2M +$11M +7,530,581 +2,651%
Millennium Management
7
Millennium Management
New York
$7.71M +$179K +122,998 +3%
BlackRock
8
BlackRock
New York
$5.18M +$189K +129,771 +4%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$4.95M +$973K +669,089 +27%
Jane Street
10
Jane Street
New York
$4.16M +$1.37M +941,634 +55%
UBS Group
11
UBS Group
Switzerland
$3.87M -$762K -524,055 -17%
Marshall Wace
12
Marshall Wace
United Kingdom
$3.71M +$1.62M +1,113,937 +88%
Susquehanna International Group
13
Susquehanna International Group
Pennsylvania
$3.31M +$1.33M +913,922 +76%
CBU
14
CIBC Bancorp USA
Illinois
$2.81M +$2.62M +1,800,000 New
Renaissance Technologies
15
Renaissance Technologies
New York
$2.5M +$1.94M +1,337,246 +508%
VFT
16
Vanguard Fiduciary Trust
Pennsylvania
$2.08M +$1.94M +1,332,284 New
Charles Schwab
17
Charles Schwab
California
$2.05M +$373K +256,175 +24%
Two Sigma Investments
18
Two Sigma Investments
New York
$1.87M +$818K +562,324 +88%
Citadel Advisors
19
Citadel Advisors
Florida
$1.71M -$896K -616,074 -36%
Goldman Sachs
20
Goldman Sachs
New York
$1.67M +$217K +149,313 +16%
State Street
21
State Street
Massachusetts
$1.5M +$115K +79,300 +9%
GCP
22
GSA Capital Partners
United Kingdom
$1.45M -$96.2K -66,146 -7%
II
23
Ishara Investments
California
$1.41M +$32K +22,000 +3%
HWAM
24
Hennion & Walsh Asset Management
New Jersey
$1.32M -$77.2K -53,084 -6%
Mackenzie Financial
25
Mackenzie Financial
Ontario, Canada
$1.21M +$1.12M +772,677 New