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Lexicon Pharmaceuticals
LXRX

Overview Fund Activity

120 hedge funds and large institutions have $240M invested in Lexicon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 31 increasing their positions, 35 reducing their positions, and 33 closing their positions.

Holders
120
Holders Change
-7
Holders Change %
-5.51%
% of All Funds
1.61%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
28
Increased
31
Reduced
35
Closed
33
Calls
$689K
Puts
$62K
Net Calls
+$627K
Net Calls Change
+$321K

Top Buyers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$36.1M
2
SC
2
Sessa Capital
New York
$2.84M
3
GCP
3
GSA Capital Partners
United Kingdom
$2.68M
4
Millennium Management
4
Millennium Management
New York
$1.55M
5
Jane Street
5
Jane Street
New York
$761K

Top Sellers

1
BlackRock
1
BlackRock
New York
$3.17M
2
SSA
2
Schonfeld Strategic Advisors
New York
$4.33M
3
State Street
3
State Street
Massachusetts
$774K
4
UBS Group
4
UBS Group
Switzerland
$379K
5
Geode Capital Management
5
Geode Capital Management
Massachusetts
$2.25M
Name Market Value Shares Shares
Change 		Shares
Change %
AG
1
Artal Group
Luxembourg
$129M 136,180,481 – –
SL
2
Siren LLC
Connecticut
$36.8M 38,918,903 – –
Fidelity Investments
3
Fidelity Investments
Massachusetts
$36.1M 38,137,535 +3,594,338 +10%
Vanguard Group
4
Vanguard Group
Pennsylvania
$8.37M 8,851,036 -706,139 -7%
SSA
5
Schonfeld Strategic Advisors
New York
$4.33M 4,576,152 -3,636,841 -44%
BlackRock
6
BlackRock
New York
$3.17M 3,354,669 -6,658,338 -66%
SC
7
Sessa Capital
New York
$2.84M 3,000,000 +3,000,000 New
GCP
8
GSA Capital Partners
United Kingdom
$2.68M 2,830,659 +2,023,167 +251%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$2.25M 2,377,694 -1,311,577 -36%
Millennium Management
10
Millennium Management
New York
$1.55M 1,643,264 +1,643,264 New
AQR Capital Management
11
AQR Capital Management
Connecticut
$1.33M 1,402,210 +228,985 +20%
Charles Schwab
12
Charles Schwab
California
$835K 883,227 -267,544 -23%
State Street
13
State Street
Massachusetts
$774K 818,621 -1,788,953 -69%
Jane Street
14
Jane Street
New York
$761K 804,667 +804,667 New
HWAM
15
Hennion & Walsh Asset Management
New Jersey
$750K 793,400 -36,654 -4%
Royal Bank of Canada
16
Royal Bank of Canada
Ontario, Canada
$732K 774,474 +771,315 +24,416%
MAM
17
Monaco Asset Management
Monaco
$503K 531,600 -202,548 -28%
HF
18
HRT Financial
New York
$461K 488,468 +488,468 New
Wellington Management Group
19
Wellington Management Group
Massachusetts
$460K 486,674 +486,674 New
Invesco
20
Invesco
Georgia
$398K 420,700 +134,941 +47%
Northern Trust
21
Northern Trust
Illinois
$394K 416,372 -693,515 -62%
Two Sigma Investments
22
Two Sigma Investments
New York
$382K 403,922 +403,922 New
UBS Group
23
UBS Group
Switzerland
$379K 400,732 -1,694,608 -81%
Group One Trading
24
Group One Trading
Illinois
$328K 346,752 -19,054 -5%
CLOS
25
Compagnie Lombard Odier SCmA
Switzerland
$312K 330,000 +220,000 +200%
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