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Lexicon Pharmaceuticals

125 hedge funds and large institutions have $299M invested in Lexicon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 23 funds opening new positions, 28 increasing their positions, 41 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

292% more call options, than puts

Call options by funds: $1.13M | Put options by funds: $289K

35% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 17

2% more funds holding

Funds holding: 123125 (+2)

1.46% more ownership

Funds ownership: 70.21%71.66% (+1.5%)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

13% less capital invested

Capital invested by funds: $344M → $299M (-$44.9M)

32% less repeat investments, than reductions

Existing positions increased: 28 | Existing positions reduced: 41

Holders
125
Holders Change
+2
Holders Change %
+1.63%
% of All Funds
1.52%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
23
Increased
28
Reduced
41
Closed
17
Calls
$1.13M
Puts
$289K
Net Calls
+$844K
Net Calls Change
-$2.49M
Name Holding Trade Value Shares
Change
Change in
Stake
AG
1
Artal Group
Luxembourg
$157M
SL
2
Siren LLC
Connecticut
$44.8M
Fidelity Investments
3
Fidelity Investments
Massachusetts
$43.5M -$1.16M -845,541 -2%
Vanguard Group
4
Vanguard Group
Pennsylvania
$11M +$116K +84,675 +0.9%
Millennium Management
5
Millennium Management
New York
$5.54M +$1.36M +991,073 +26%
BlackRock
6
BlackRock
New York
$3.67M -$278K -202,524 -6%
UBS Group
7
UBS Group
Switzerland
$3.46M +$3.65M +2,654,315 +752%
SC
8
Sessa Capital
New York
$3.45M
Geode Capital Management
9
Geode Capital Management
Massachusetts
$2.88M +$140K +102,099 +4%
CIBC Private Wealth Group
10
CIBC Private Wealth Group
Georgia
$2.24M -$618K -450,257 -19%
Jane Street
11
Jane Street
New York
$1.98M +$1.74M +1,267,774 +278%
Citadel Advisors
12
Citadel Advisors
Florida
$1.97M -$1.27M -923,052 -35%
Marshall Wace
13
Marshall Wace
United Kingdom
$1.45M +$1.73M +1,262,367 New
Susquehanna International Group
14
Susquehanna International Group
Pennsylvania
$1.39M +$337K +245,182 +25%
Charles Schwab
15
Charles Schwab
California
$1.21M -$123K -89,509 -8%
GCP
16
GSA Capital Partners
United Kingdom
$1.15M -$284K -206,671 -17%
Goldman Sachs
17
Goldman Sachs
New York
$1.06M +$1.18M +861,857 +1,452%
HWAM
18
Hennion & Walsh Asset Management
New Jersey
$1.04M +$168K +122,010 +16%
State Street
19
State Street
Massachusetts
$1.02M +$6.34K +4,617 +0.5%
II
20
Ishara Investments
California
$1.01M +$1.21M +880,000 New
Two Sigma Investments
21
Two Sigma Investments
New York
$733K +$108K +78,300 +14%
Acadian Asset Management
22
Acadian Asset Management
Massachusetts
$732K +$829K +603,225 +1,635%
Invesco
23
Invesco
Georgia
$684K +$101K +73,480 +14%
Northern Trust
24
Northern Trust
Illinois
$474K +$58.2K +42,370 +11%
CLOS
25
Compagnie Lombard Odier SCmA
Switzerland
$472K