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Lexicon Pharmaceuticals
LXRX

Overview Fund Activity

127 hedge funds and large institutions have $122M invested in Lexicon Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 32 funds opening new positions, 34 increasing their positions, 32 reducing their positions, and 29 closing their positions.

Holders
127
Holders Change
+1
Holders Change %
+0.79%
% of All Funds
1.73%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
32
Increased
34
Reduced
32
Closed
29
Calls
$358K
Puts
$52K
Net Calls
+$306K
Net Calls Change
-$78K

Top Buyers

1
CIBC Private Wealth Group
1
CIBC Private Wealth Group
Georgia
$1.12M
2
UBS Group
2
UBS Group
Switzerland
$966K
3
AQR Capital Management
3
AQR Capital Management
Connecticut
$541K
4
GCP
4
GSA Capital Partners
United Kingdom
$372K
5
MAM
5
Monaco Asset Management
Monaco
$338K

Top Sellers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$15.9M
2
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$0
3
NCM
3
Nantahala Capital Management
Connecticut
$212K
4
NMC
4
NEA Management Company
Maryland
$0
5
PA
5
Pinnacle Associates
New York
$25K
Name Market Value Shares Shares
Change 		Shares
Change %
AG
1
Artal Group
Luxembourg
$62.6M 136,180,481 – –
SL
2
Siren LLC
Connecticut
$17.9M 38,918,903 – –
Fidelity Investments
3
Fidelity Investments
Massachusetts
$15.9M 34,543,197 -17,427,258 -34%
BlackRock
4
BlackRock
New York
$4.61M 10,013,007 -320,151 -3%
Vanguard Group
5
Vanguard Group
Pennsylvania
$4.41M 9,557,175 -324,553 -3%
SSA
6
Schonfeld Strategic Advisors
New York
$3.78M 8,212,993 +654,372 +9%
Geode Capital Management
7
Geode Capital Management
Massachusetts
$1.7M 3,689,271 +168,016 +5%
State Street
8
State Street
Massachusetts
$1.2M 2,607,574 -110,674 -4%
CIBC Private Wealth Group
9
CIBC Private Wealth Group
Georgia
$1.12M 2,240,000 +2,240,000 New
UBS Group
10
UBS Group
Switzerland
$966K 2,095,340 +1,409,223 +205%
IC
11
Ikarian Capital
Texas
$653K 1,417,952 -132,048 -9%
AQR Capital Management
12
AQR Capital Management
Connecticut
$541K 1,173,225 +1,173,225 New
Charles Schwab
13
Charles Schwab
California
$530K 1,150,771 -40,320 -3%
TCM
14
Tang Capital Management
California
$530K 1,150,268 +300,000 +35%
Northern Trust
15
Northern Trust
Illinois
$511K 1,109,887 -198,764 -15%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$438K 951,135 +400,244 +73%
HWAM
17
Hennion & Walsh Asset Management
New Jersey
$382K 830,054 -33,201 -4%
GCP
18
GSA Capital Partners
United Kingdom
$372K 807,492 +807,492 New
MAM
19
Monaco Asset Management
Monaco
$338K 734,148 +734,148 New
Morgan Stanley
20
Morgan Stanley
New York
$296K 641,629 +115,479 +22%
Acadian Asset Management
21
Acadian Asset Management
Massachusetts
$263K 573,688 +573,688 New
BP
22
BBR Partners
New York
$263K 570,000 +100,000 +21%
NCM
23
Nantahala Capital Management
Connecticut
$212K 460,850 -6,143,300 -93%
BFM
24
Boothbay Fund Management
New York
$210K 454,891 -25,931 -5%
VIA
25
Virtus Investment Advisers
Connecticut
$201K 436,672 +436,672 New
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