LXRX icon

Lexicon Pharmaceuticals
LXRX

Overview Fund Activity

122 hedge funds and large institutions have $243M invested in Lexicon Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 32 increasing their positions, 36 reducing their positions, and 33 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
122
Holders Change
-5
Holders Change %
-3.94%
% of All Funds
1.64%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
28
Increased
32
Reduced
36
Closed
33
Calls
$805K
Puts
$145K
Net Calls
+$660K
Net Calls Change
+$354K

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
$36.1M
2
SC
Sessa Capital
New York
$2.84M
3
GCP
GSA Capital Partners
United Kingdom
$2.68M
4
Millennium Management
Millennium Management
New York
$1.55M
5
Jane Street
Jane Street
New York
$761K

Top Sellers

1
BlackRock
BlackRock
New York
$3.17M
2
SSA
Schonfeld Strategic Advisors
New York
$4.33M
3
State Street
State Street
Massachusetts
$774K
4
UBS Group
UBS Group
Switzerland
$379K
5
Geode Capital Management
Geode Capital Management
Massachusetts
$2.25M
Name Holding Trade Value Shares
Change 		Shares
Change %
AG
1
Artal Group
Luxembourg
$129M – – –
SL
2
Siren LLC
Connecticut
$36.8M – – –
Fidelity Investments
3
Fidelity Investments
Massachusetts
$36.1M +$3.4M +3,594,338 +10%
Vanguard Group
4
Vanguard Group
Pennsylvania
$8.37M -$668K -706,139 -7%
SSA
5
Schonfeld Strategic Advisors
New York
$4.33M -$3.44M -3,636,841 -44%
BlackRock
6
BlackRock
New York
$3.17M -$6.3M -6,658,338 -66%
SC
7
Sessa Capital
New York
$2.84M +$2.84M +3,000,000 New
GCP
8
GSA Capital Partners
United Kingdom
$2.68M +$1.91M +2,023,167 +251%
CIBC Private Wealth Group
9
CIBC Private Wealth Group
Georgia
$2.32M +$199K +210,400 +9%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$2.25M -$1.24M -1,311,577 -36%
Millennium Management
11
Millennium Management
New York
$1.55M +$1.55M +1,643,264 New
AQR Capital Management
12
AQR Capital Management
Connecticut
$1.33M +$217K +228,985 +20%
Charles Schwab
13
Charles Schwab
California
$835K -$253K -267,544 -23%
State Street
14
State Street
Massachusetts
$774K -$1.69M -1,788,953 -69%
Jane Street
15
Jane Street
New York
$761K +$761K +804,667 New
HWAM
16
Hennion & Walsh Asset Management
New Jersey
$750K -$34.7K -36,654 -4%
Royal Bank of Canada
17
Royal Bank of Canada
Ontario, Canada
$732K +$729K +771,315 +24,416%
Susquehanna International Group
18
Susquehanna International Group
Pennsylvania
$715K -$185K -195,483 -21%
MAM
19
Monaco Asset Management
Monaco
$503K -$192K -202,548 -28%
HF
20
HRT Financial
New York
$461K +$461K +488,468 New
Wellington Management Group
21
Wellington Management Group
Massachusetts
$460K +$460K +486,674 New
Invesco
22
Invesco
Georgia
$398K +$128K +134,941 +47%
Northern Trust
23
Northern Trust
Illinois
$394K -$656K -693,515 -62%
Two Sigma Investments
24
Two Sigma Investments
New York
$382K +$382K +403,922 New
UBS Group
25
UBS Group
Switzerland
$379K -$1.6M -1,694,608 -81%
1
2 3 4 5