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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+25.71%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$336M
AUM Growth
-$103M
Cap. Flow
-$126M
Cap. Flow %
-37.49%
Top 10 Hldgs %
58.57%
Holding
65
New
22
Increased
6
Reduced
11
Closed
14

Top Buys

Rank Stock Value
1
LH icon
Labcorp
LH
+$13.4M
2
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$12M
3
MDT icon
Medtronic
MDT
+$8.96M
4
TYRA icon
Tyra Biosciences
TYRA
+$8.79M
5
OGN icon
Organon & Co
OGN
+$8.22M

Top Sells

Rank Stock Value
1
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$85.3M
2
GRCL
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
+$50.2M
3
IMGN
Immunogen Inc
IMGN
+$19.1M
4
UTHR icon
United Therapeutics
UTHR
+$17.6M
5
CI icon
Cigna
CI
+$13.3M

Sector Composition

Rank Sector Weight
1 Healthcare 85.46%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CMAXW
51
DELISTED
CareMax, Inc. Warrant
CMAXW
$302 ﹤0.01%
12,808
– –
CMPS
52
Compass Pathways
CMPS
$1.83B
– –
-251,532
Closed -$2.2M
CRBP icon
53
Corbus Pharmaceuticals
CRBP
$180M
– –
-150,000
Closed -$906K
INGN icon
54
Inogen
INGN
$176M
– –
-52,794
Closed -$290K
NEOG icon
55
PUT
Neogen
NEOG
$2.46B
– –
-427,000
Closed -$8.59M
PTGX icon
56
Protagonist Therapeutics
PTGX
$9.4B
– –
-460,044
Closed -$10.5M
SRPT icon
57
PUT
Sarepta Therapeutics
SRPT
$1.77B
– –
-141,300
Closed -$13.6M
UTHR icon
58
United Therapeutics
UTHR
$22.6B
– –
-80,050
Closed -$17.6M
VNDA icon
59
Vanda Pharmaceuticals
VNDA
$308M
– –
-97,616
Closed -$412K
GRCL
60
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
– –
-5,001,580
Closed -$50.2M
IMGN
61
DELISTED
Immunogen Inc
IMGN
– –
-644,366
Closed -$19.1M
MRTX
62
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
– –
-1,451,925
Closed -$85.3M
HARP
63
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
– –
-297,936
Closed -$3.39M
MACK
64
DELISTED
Merrimack Pharmaceuticals, Inc.
MACK
– –
-288,466
Closed -$3.87M
CMAX
65
DELISTED
CareMax, Inc. Class A Common Stock
CMAX
– –
-1,025
Closed -$15.3K
1 2
3

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Sio Capital Management's Q1 2024 Portfolio in Review

As of Q1 2024, Sio Capital Management held 65 positions worth $336M, down 24% from $439M the previous quarter. Its ten largest holdings account for 59% of the portfolio.

Sio Capital Management withdrew a net $126M in Q1 2024, closing 14 positions and reducing 11 holdings. Its most notable exit was Mirati Therapeutics, Inc. Common Stock, an estimated $85.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 85% of assets, down from 88% a quarter earlier.

Against the trend, Sio Capital Management opened a new position in Madrigal Pharmaceuticals worth $13.6M.

  • Sio Capital Management's largest Q1 2024 buy was Madrigal Pharmaceuticals: 51,000 shares worth $13.6M.
  • Sio Capital Management added most to Labcorp in Q1 2024, an estimated $13.4M increase.
  • Sio Capital Management's biggest Q1 2024 reduction was Cigna, cutting an estimated $13.3M.
  • Sio Capital Management fully exited Mirati Therapeutics, Inc. Common Stock in Q1 2024, selling an estimated $85.3M.
  • Sio Capital Management's ten largest holdings make up 59% of its $336M portfolio in Q1 2024.
  • Sio Capital Management opened 22 new positions and closed 14 in Q1 2024.
  • Sio Capital Management's portfolio value fell 24% quarter-over-quarter to $336M.

Based on Sio Capital Management's 13F filing for Q1 2024, filed 15 May 2024.