Simplex Trading
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Simplex Trading’s uniQure QURE Stock Holding History

Simplex Trading’s Portfolio QURE Stock Details QURE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$10.7M Buy
657,100
+181,800
+38% +$3.68M 0.01% 672
2025
Q4 		$11.4M Buy
475,300
+242,700
+104% +$9.37M 0.01% 775
2025
Q3 		$13.6M Sell
232,600
-110,100
-32% -$2M 0.01% 794
2025
Q2 		$4.78M Buy
342,700
+282,000
+465% +$3.79M ﹤0.01% 1383
2025
Q1 		$643K Sell
60,700
-139,700
-70% -$1.96M ﹤0.01% 3123
2024
Q4 		$3.54M Buy
200,400
+189,200
+1,689% +$1.63M ﹤0.01% 1726
2024
Q3 		$55K Sell
11,200
-99,300
-90% -$647K ﹤0.01% 5806
2024
Q2 		$495K Buy
110,500
+51,200
+86% +$249K ﹤0.01% 3676
2024
Q1 		$308K Buy
59,300
+11,900
+25% +$68.3K ﹤0.01% 4357
2023
Q4 		$320K Buy
47,400
+3,200
+7% +$21.1K ﹤0.01% 4156
2023
Q3 		$296K Sell
44,200
-40,800
-48% -$367K ﹤0.01% 3953
2023
Q2 		$974K Buy
85,000
+28,700
+51% +$544K ﹤0.01% 2627
2023
Q1 		$1.13M Sell
56,300
-4,100
-7% -$86K ﹤0.01% 2485
2022
Q4 		$1.37M Buy
60,400
+52,200
+637% +$1.13M ﹤0.01% 2176
2022
Q3 		$153K Buy
8,200
+5,400
+193% +$114K ﹤0.01% 4965
2022
Q2 		$52K Sell
2,800
-3,200
-53% -$50.9K ﹤0.01% 6443
2022
Q1 		$108K Sell
6,000
-42,800
-88% -$747K ﹤0.01% 6032
2021
Q4 		$1.01M Buy
48,800
+10,900
+29% +$313K ﹤0.01% 2834
2021
Q3 		$1.18M Buy
37,900
+100
+0.3% +$3.05K ﹤0.01% 2832
2021
Q2 		$1.16M Buy
37,800
+37,542
+14,551% +$1.26M ﹤0.01% 2886
2021
Q1 		$869K Buy
258
+124
+93% +$4.44K ﹤0.01% 2578
2020
Q4 		$484K Buy
134
+29
+28% +$1.22K ﹤0.01% 3470
2020
Q3 		$386K Sell
105
-6
-5% -$246 ﹤0.01% 3300
2020
Q2 		$500K Sell
111
-53
-32% -$3.13K ﹤0.01% 2908
2020
Q1 		$778K Sell
164
-28
-15% -$1.61K ﹤0.01% 2124
2019
Q4 		$1.38M Sell
192
-162
-46% -$8.89K ﹤0.01% 1797
2019
Q3 		$1.39M Buy
354
+270
+321% +$15.6K ﹤0.01% 1641
2019
Q2 		$656K Buy
84
+46
+121% +$2.93K ﹤0.01% 2321
2019
Q1 		$226K Sell
38
-10
-21% -$447 ﹤0.01% 3474
2018
Q4 		$138K Sell
48
-19
-28% -$529 ﹤0.01% 3530
2018
Q3 		$243K Buy
67
+30
+81% +$1.12K ﹤0.01% 3430
2018
Q2 		$139K Sell
37
-85
-70% -$2.72K ﹤0.01% 3902
2018
Q1 		$45K Sell
122
-14
-10% -$305 ﹤0.01% 2549
2017
Q4 		$81K Buy
136
+36
+36% +$548 ﹤0.01% 1984
2017
Q3 		$9K Buy
+100
New +$805 ﹤0.01% 3882
2016
Q2 		– Sell
-170
Closed -$14K – 6342
2016
Q1 		$14K Buy
170
+16
+10% +$236 ﹤0.01% 3153
2015
Q4 		$30K Sell
154
-20
-11% -$371 ﹤0.01% 2340
2015
Q3 		$55K Buy
174
+172
+8,600% +$4.53K ﹤0.01% 1909
2015
Q2 		$1K Buy
+2
New +$57 ﹤0.01% 4767

Other funds holding QURE

ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Aberdeen Group
Aberdeen Group Edinburgh, United Kingdom $61.9B AUM 29.81% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
MB
MPM BioImpact Boston, Massachusetts $1.29B AUM 141.72% 1-Year Est. Return

Simplex Trading's QURE Position: Q1 2026 in Review

Simplex Trading increased its uniQure (QURE) stake by 109% in Q1 2026, buying an estimated $2.45M and bringing the position to 231,769 shares worth $3.79M. The position accounts for ﹤0.01% of the portfolio, ranked #1316.

Simplex Trading first reported a position in QURE in Q2 2016 and has held it in 33 quarters since. The position peaked at $3.97M in Q3 2025. 212 funds tracked by Wall St. Rank hold QURE as of Q1 2026.

  • Simplex Trading held 231,769 shares of uniQure worth $3.79M as of Q1 2026.
  • Simplex Trading bought 121,094 uniQure shares in Q1 2026, an estimated $2.45M.
  • uniQure made up ﹤0.01% of Simplex Trading's portfolio in Q1 2026, its #1316 holding.
  • Simplex Trading first reported a position in uniQure in Q2 2016 and has held it in 33 quarters since.
  • Simplex Trading's uniQure position peaked at $3.97M in Q3 2025.
  • 212 funds tracked by Wall St. Rank held uniQure as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.