Simplex Trading
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Simplex Trading’s Amylyx Pharmaceuticals AMLX Stock Holding History

Simplex Trading’s Portfolio AMLX Stock Details AMLX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$455K Buy
32,700
+4,500
+16% +$63.3K ﹤0.01% 3377
2025
Q4 		$341K Sell
28,200
-43,300
-61% -$588K ﹤0.01% 3695
2025
Q3 		$971K Buy
71,500
+46,500
+186% +$438K ﹤0.01% 3078
2025
Q2 		$160K Buy
25,000
+19,000
+317% +$92.4K ﹤0.01% 4740
2025
Q1 		$21K Sell
6,000
-34,100
-85% -$121K ﹤0.01% 6527
2024
Q4 		$151K Buy
40,100
+31,800
+383% +$150K ﹤0.01% 4779
2024
Q3 		$26K Sell
8,300
-13,300
-62% -$29.9K ﹤0.01% 6454
2024
Q2 		$41K Sell
21,600
-358,700
-94% -$695K ﹤0.01% 6264
2024
Q1 		$1.08M Buy
380,300
+291,700
+329% +$3.82M ﹤0.01% 3039
2023
Q4 		$1.3M Sell
88,600
-75,900
-46% -$1.16M ﹤0.01% 2765
2023
Q3 		$3.01M Sell
164,500
-38,300
-19% -$810K ﹤0.01% 1729
2023
Q2 		$4.37M Buy
202,800
+13,500
+7% +$365K ﹤0.01% 1406
2023
Q1 		$5.55M Buy
189,300
+169,200
+842% +$5.88M ﹤0.01% 1238
2022
Q4 		$742K Sell
20,100
-241,700
-92% -$8.58M ﹤0.01% 2764
2022
Q3 		$7.37M Buy
261,800
+187,300
+251% +$4.67M 0.01% 943
2022
Q2 		$1.43M Buy
74,500
+41,400
+125% +$492K ﹤0.01% 2213
2022
Q1 		$425K Buy
+33,100
New +$748K ﹤0.01% 4045

Other funds holding AMLX

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
SVCM
Saturn V Capital Management Austin, Texas $552M AUM 551.78% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Adage Capital Partners
Adage Capital Partners Boston, Massachusetts $64.8B AUM 42.7% 1-Year Est. Return
FLAM
First Light Asset Management Edina, Minnesota $1.12B AUM 114.45% 1-Year Est. Return

Simplex Trading's AMLX Position: Q1 2026 in Review

Simplex Trading sold out of Amylyx Pharmaceuticals (AMLX) in Q1 2026, closing a stake of 3,727 shares — an estimated $52.4K sold.

Simplex Trading first reported a position in AMLX in Q1 2022 and held it in 13 quarters. The position peaked at $3.28M in Q3 2022. 171 funds tracked by Wall St. Rank hold AMLX as of Q1 2026.

  • Simplex Trading reported no remaining Amylyx Pharmaceuticals position as of Q1 2026 after selling out during the quarter.
  • Simplex Trading sold 3,727 Amylyx Pharmaceuticals shares in Q1 2026, an estimated $52.4K.
  • Simplex Trading first reported a position in Amylyx Pharmaceuticals in Q1 2022 and held it in 13 quarters.
  • Simplex Trading's Amylyx Pharmaceuticals position peaked at $3.28M in Q3 2022.
  • 171 funds tracked by Wall St. Rank held Amylyx Pharmaceuticals as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.