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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-17.44%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$3.87B
AUM Growth
-$961M
Cap. Flow
+$318M
Cap. Flow %
8.21%
Top 10 Hldgs %
45.33%
Holding
116
New
10
Increased
28
Reduced
12
Closed
9

Top Buys

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$78.8M
2
IMCR icon
Immunocore
IMCR
+$69.4M
3
TMO icon
Thermo Fisher Scientific
TMO
+$34.4M
4
ARGX icon
argenx
ARGX
+$34M
5
MASI
Masimo
MASI
+$29.9M

Top Sells

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$36.9M
2
AXNX
Axonics, Inc. Common Stock
AXNX
+$30.9M
3
LONA
LeonaBio Inc
LONA
+$25.7M
4
ITOS
iTeos Therapeutics
ITOS
+$15.7M
5
VCEL icon
Vericel Corp
VCEL
+$14.6M

Sector Composition

Rank Sector Weight
1 Healthcare 98.86%
2 Financials 0.75%
3 Industrials 0.27%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ISO
101
DELISTED
IsoPlexis Corporation Common Stock
ISO
$788K 0.02%
365,000
– –
RCEL icon
102
Avita Medical
RCEL
$240M
$507K 0.01%
106,667
– –
UTRS
103
DELISTED
Minerva Surgical, Inc. Common Stock
UTRS
$390K 0.01%
8,300
– –
OMIC
104
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$382K 0.01%
3,333
– –
TBIO
105
DELISTED
Telesis Bio, Inc. Common Stock
TBIO
$180K ﹤0.01%
5,556
-5,555
-50% -$384K
RCOR.WS
106
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$21K ﹤0.01%
350,000
– –
MSACW
107
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
$6K ﹤0.01%
33,331
– –
ADVM
108
DELISTED
Adverum Biotechnologies
ADVM
– –
-22,373
Closed -$293K
APLS
109
DELISTED
Apellis Pharmaceuticals
APLS
– –
-51,194
Closed -$2.6M
LONA
110
LeonaBio Inc
LONA
$72.1M
– –
-190,656
Closed -$25.7M
CNTB
111
Connect Biopharma Holdings
CNTB
$139M
– –
-446,564
Closed -$1.35M
ITOS
112
DELISTED
iTeos Therapeutics
ITOS
– –
-489,014
Closed -$15.7M
PRQR icon
113
ProQR Therapeutics
PRQR
$265M
– –
-7,019,610
Closed -$6.35M
SOPH icon
114
SOPHiA GENETICS
SOPH
$647M
– –
-226,589
Closed -$1.75M
NSTG
115
DELISTED
NanoString Technologies, Inc.
NSTG
– –
-404,029
Closed -$14M
ZY
116
DELISTED
Zymergen Inc. Common Stock
ZY
– –
-70,000
Closed -$202K
1 2 3 4
5

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RTW Investments's Q2 2022 Portfolio in Review

As of Q2 2022, RTW Investments held 116 positions worth $3.87B, down 20% from $4.83B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $318M of net new capital in Q2 2022, opening 10 new positions and adding to 28 existing holdings. Its largest new stake was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, down from 99% a quarter earlier, followed by Financials and Industrials.

On the sell side, the largest reduction was Globus Medical, an estimated $36.9M trimmed.

  • RTW Investments's largest Q2 2022 buy was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.
  • RTW Investments added most to Immunocore in Q2 2022, an estimated $69.4M increase.
  • RTW Investments's biggest Q2 2022 reduction was Globus Medical, cutting an estimated $36.9M.
  • RTW Investments fully exited LeonaBio Inc in Q2 2022, selling an estimated $25.7M.
  • RTW Investments's ten largest holdings make up 45% of its $3.87B portfolio in Q2 2022.
  • RTW Investments opened 10 new positions and closed 9 in Q2 2022.
  • RTW Investments's portfolio value fell 20% quarter-over-quarter to $3.87B.

Based on RTW Investments's 13F filing for Q2 2022, filed 15 Aug 2022.