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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+9.72%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$6.63B
AUM Growth
+$221M
Cap. Flow
-$85.5M
Cap. Flow %
-1.29%
Top 10 Hldgs %
45.03%
Holding
125
New
14
Increased
22
Reduced
8
Closed
12

Top Buys

Rank Stock Value
1
EPIX
ESSA Pharma
EPIX
+$80.5M
2
MASI
Masimo
MASI
+$52.8M
3
RGNX icon
Regenxbio
RGNX
+$48M
4
GHRS icon
GH Research
GHRS
+$44.3M
5
GH icon
Guardant Health
GH
+$41.5M

Top Sells

Rank Stock Value
1
CERN
Cerner Corp
CERN
+$128M
2
ARVN icon
Arvinas
ARVN
+$107M
3
IMVT icon
Immunovant
IMVT
+$102M
4
TBIO
Translate Bio, Inc. Common Stock
TBIO
+$72.3M
5
CRIS icon
Curis
CRIS
+$41M

Sector Composition

Rank Sector Weight
1 Healthcare 88.48%
2 Financials 0.38%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ZY
101
DELISTED
Zymergen Inc. Common Stock
ZY
$2.8M 0.04%
+70,000
New +$2.76M
OMIC
102
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$2.75M 0.04%
+3,333
New +$2.58M
TWST icon
103
Twist Bioscience
TWST
$7.19B
$2.46M 0.04%
18,473
– –
CEREW
104
DELISTED
Cerevel Therapeutics Holdings, Inc. Warrant
CEREW
$2.4M 0.04%
166,666
– –
PROF
105
Profound Medical
PROF
$275M
$2M 0.03%
122,098
– –
BOLT icon
106
Bolt Biotherapeutics
BOLT
$7.71M
$1.95M 0.03%
6,318
-1,182
-16% -$480K
AKYA
107
DELISTED
Akoya BioSciences
AKYA
$1.93M 0.03%
+100,000
New +$2.06M
BDSX icon
108
Biodesix
BDSX
$245M
$1.65M 0.02%
6,250
– –
MASS icon
109
908 Devices
MASS
$348M
$1.55M 0.02%
40,000
– –
ELUT icon
110
Elutia
ELUT
$38.3M
$1.2M 0.02%
125,000
– –
BNR
111
Burning Rock Biotech
BNR
$93.7M
$884K 0.01%
3,000
– –
BIOR
112
DELISTED
Biora Therapeutics, Inc. Common Stock
BIOR
$357K 0.01%
400
– –
MSACW
113
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
$34K ﹤0.01%
+33,331
New +$26.4K
ARVN icon
114
Arvinas
ARVN
$570M
– –
-1,622,799
Closed -$107M
BCAB icon
115
BioAtla
BCAB
$5.64M
– –
-200
Closed -$508K
CRIS icon
116
Curis
CRIS
$8.24M
– –
-9,049
Closed -$41M
IMVT icon
117
Immunovant
IMVT
$8.22B
– –
-6,356,743
Closed -$102M
KURA icon
118
Kura Oncology
KURA
$842M
– –
-1,081,912
Closed -$30.6M
NUVB icon
119
Nuvation Bio
NUVB
$2.28B
– –
-300,000
Closed -$3.13M
NUVB.WS
120
DELISTED
Nuvation Bio Inc Warrants
NUVB.WS
– –
-100,000
Closed -$267K
SEER icon
121
Seer Inc
SEER
$122M
– –
-4,000
Closed -$200K
CERN
122
DELISTED
Cerner Corp
CERN
– –
-1,774,485
Closed -$128M
TBIO
123
DELISTED
Translate Bio, Inc. Common Stock
TBIO
– –
-4,382,199
Closed -$72.3M
VINCW
124
DELISTED
Vincerx Pharma, Inc. Warrant
VINCW
– –
-500,000
Closed -$2.02M
MSACU
125
DELISTED
Medicus Sciences Acquisition Corp. Unit
MSACU
– –
-300,000
Closed -$2.96M
1 2 3 4
5

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RTW Investments's Q2 2021 Portfolio in Review

As of Q2 2021, RTW Investments held 125 positions worth $6.63B, up 3.5% from $6.41B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments's Q2 2021 filing shows 14 new, 22 increased, 8 reduced and 12 closed positions. Its largest new stake was GH Research: 2,168,957 shares worth $42.7M. The largest sale was Cerner Corp, an estimated $128M.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 88% a quarter earlier, followed by Financials.

  • RTW Investments's largest Q2 2021 buy was GH Research: 2,168,957 shares worth $42.7M.
  • RTW Investments added most to ESSA Pharma in Q2 2021, an estimated $80.5M increase.
  • RTW Investments's biggest Q2 2021 reduction was Rocket Pharmaceuticals, cutting an estimated $31.5M.
  • RTW Investments fully exited Cerner Corp in Q2 2021, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 45% of its $6.63B portfolio in Q2 2021.
  • RTW Investments opened 14 new positions and closed 12 in Q2 2021.
  • RTW Investments's portfolio value rose 3.5% quarter-over-quarter to $6.63B.

Based on RTW Investments's 13F filing for Q2 2021, filed 13 Aug 2021.