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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+60.02%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$5.96B
AUM Growth
+$1.81B
Cap. Flow
+$286M
Cap. Flow %
4.79%
Top 10 Hldgs %
47.57%
Holding
116
New
25
Increased
35
Reduced
12
Closed
14

Top Buys

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$94.3M
2
TARS icon
Tarsus Pharmaceuticals
TARS
+$70.2M
3
CCCC icon
C4 Therapeutics
CCCC
+$62.3M
4
ARVN icon
Arvinas
ARVN
+$61.8M
5
ILMN icon
Illumina
ILMN
+$61.2M

Sector Composition

Rank Sector Weight
1 Healthcare 94%
2 Financials 0.18%
3 Materials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
BCAB icon
101
BioAtla
BCAB
$5.74M
$340K 0.01%
+200
New +$334K
SEER icon
102
Seer Inc
SEER
$120M
$225K ﹤0.01%
+4,000
New +$254K
ADAP
103
DELISTED
Adaptimmune Therapeutics
ADAP
-2,617,626
Closed -$20.9M
ALT icon
104
Altimmune
ALT
$599M
-1,334,940
Closed -$17.6M
ARCT icon
105
Arcturus Therapeutics
ARCT
$211M
-251,236
Closed -$10.8M
BAX icon
106
Baxter International
BAX
$14.2B
-1,077,268
Closed -$86.6M
EQ icon
107
Equillium
EQ
$133M
-1,004,784
Closed -$5.8M
INCY icon
108
Incyte
INCY
$24.4B
-334,144
Closed -$30M
QURE icon
109
uniQure
QURE
$3.22B
-158,479
Closed -$5.84M
TMDX icon
110
Transmedics
TMDX
$2.91B
-503,266
Closed -$6.93M
VXRT
111
DELISTED
Vaxart
VXRT
-3,517,345
Closed -$23.4M
QTTB icon
112
Q32 Bio
QTTB
$464M
-139,884
Closed -$26.9M
AMRS
113
DELISTED
Amyris Inc.
AMRS
-5,161,347
Closed -$15.1M
LSACU
114
DELISTED
LifeSci Acquisition Corp. Unit 1 COM & 1 WT
LSACU
-500,000
Closed -$6.8M
MYOK
115
DELISTED
MyoKardia, Inc. Common Stock
MYOK
-936,931
Closed -$128M
ARYBU
116
DELISTED
ARYA Sciences Acquisition Corp II Unit
ARYBU
-500,000
Closed -$5.5M

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RTW Investments's Q4 2020 Portfolio in Review

As of Q4 2020, RTW Investments held 116 positions worth $5.96B, up 44% from $4.15B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $286M of net new capital in Q4 2020, opening 25 new positions and adding to 35 existing holdings. Its largest new stake was Globus Medical: 1,640,859 shares worth $107M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 93% a quarter earlier, followed by Financials and Materials.

On the sell side, the largest reduction was OraSure Technologies, an estimated $24.8M trimmed.

  • RTW Investments's largest Q4 2020 buy was Globus Medical: 1,640,859 shares worth $107M.
  • RTW Investments added most to Illumina in Q4 2020, an estimated $61.2M increase.
  • RTW Investments's biggest Q4 2020 reduction was OraSure Technologies, cutting an estimated $24.8M.
  • RTW Investments fully exited MyoKardia, Inc. Common Stock in Q4 2020, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 48% of its $5.96B portfolio in Q4 2020.
  • RTW Investments opened 25 new positions and closed 14 in Q4 2020.
  • RTW Investments's portfolio value rose 44% quarter-over-quarter to $5.96B.

Based on RTW Investments's 13F filing for Q4 2020, filed 16 Feb 2021.