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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+32.04%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$6.4B
AUM Growth
+$1.66B
Cap. Flow
+$453M
Cap. Flow %
7.07%
Top 10 Hldgs %
53.23%
Holding
81
New
14
Increased
12
Reduced
20
Closed
17

Top Buys

Rank Stock Value
1
ARVN icon
Arvinas
ARVN
+$98.5M
2
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$88.5M
3
CRGX
CARGO Therapeutics
CRGX
+$87.8M
4
ALKS icon
Alkermes
ALKS
+$78.3M
5
ARGX icon
argenx
ARGX
+$74.6M

Sector Composition

Rank Sector Weight
1 Healthcare 99.98%
2 Financials 0.02%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
VKTX icon
76
Viking Therapeutics
VKTX
$4B
-259,400
Closed -$2.87M
AXNX
77
DELISTED
Axonics, Inc. Common Stock
AXNX
-442,487
Closed -$24.8M
OLK
78
DELISTED
Olink Holding AB (publ) American Depositary Shares
OLK
-163,652
Closed -$2.41M
DMTK
79
DELISTED
DermTech, Inc. Common Stock
DMTK
-2,718,356
Closed -$3.91M
RYZB
80
DELISTED
RayzeBio, Inc. Common Stock
RYZB
-46,300
Closed -$1.03M
MIRO
81
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
-445,222
Closed -$583K

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RTW Investments's Q4 2023 Portfolio in Review

As of Q4 2023, RTW Investments held 81 positions worth $6.4B, up 35% from $4.74B the previous quarter. Its ten largest holdings account for 53% of the portfolio.

RTW Investments deployed $453M of net new capital in Q4 2023, opening 14 new positions and adding to 12 existing holdings. Its largest new stake was Arvinas: 4,213,483 shares worth $173M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Thermo Fisher Scientific, an estimated $116M trimmed.

  • RTW Investments's largest Q4 2023 buy was Arvinas: 4,213,483 shares worth $173M.
  • RTW Investments added most to Madrigal Pharmaceuticals in Q4 2023, an estimated $88.5M increase.
  • RTW Investments's biggest Q4 2023 reduction was Thermo Fisher Scientific, cutting an estimated $116M.
  • RTW Investments fully exited MoonLake Immunotherapeutics in Q4 2023, selling an estimated $28.5M.
  • RTW Investments's ten largest holdings make up 53% of its $6.4B portfolio in Q4 2023.
  • RTW Investments opened 14 new positions and closed 17 in Q4 2023.
  • RTW Investments's portfolio value rose 35% quarter-over-quarter to $6.4B.

Based on RTW Investments's 13F filing for Q4 2023, filed 14 Feb 2024.