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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+5.65%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.8B
AUM Growth
-$96.5M
Cap. Flow
+$4.8M
Cap. Flow %
0.1%
Top 10 Hldgs %
55.46%
Holding
84
New
7
Increased
20
Reduced
15
Closed
24

Top Buys

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$87.1M
2
BRKR icon
Bruker
BRKR
+$85.7M
3
PTCT icon
PTC Therapeutics
PTCT
+$67.6M
4
AXSM icon
Axsome Therapeutics
AXSM
+$52.6M
5
OBIO icon
Orchestra BioMed
OBIO
+$47.7M

Top Sells

Rank Stock Value
1
TMO icon
Thermo Fisher Scientific
TMO
+$81.8M
2
GMED icon
Globus Medical
GMED
+$55.5M
3
RGNX icon
Regenxbio
RGNX
+$41.9M
4
ILMN icon
Illumina
ILMN
+$39.6M
5
BCYC
Bicycle Therapeutics
BCYC
+$37.3M

Sector Composition

Rank Sector Weight
1 Healthcare 99.97%
2 Financials 0.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
SNCE
76
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
– –
-129,305
Closed -$1.07M
ARYE
77
DELISTED
ARYA Sciences Acquisition Corp V Class A Ordinary Shares
ARYE
– –
-500,000
Closed -$5.04M
ISEE
78
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
– –
-821,288
Closed -$17.6M
JNCE
79
DELISTED
Jounce Therapeutics, Inc. Common Stock
JNCE
– –
-5,106,341
Closed -$5.67M
SMIHU
80
DELISTED
Summit Healthcare Acquisition Corp. Units
SMIHU
– –
-500,000
Closed -$5.06M
CINC
81
DELISTED
CinCor Pharma, Inc. Common Stock
CINC
– –
-1,389,705
Closed -$17.1M
MSACW
82
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
– –
-33,331
Closed -$3K
MSAC
83
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
– –
-300,000
Closed -$3.02M
OYST
84
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
– –
-2,304,977
Closed -$25.7M
1 2 3
4

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RTW Investments's Q1 2023 Portfolio in Review

As of Q1 2023, RTW Investments held 84 positions worth $4.8B, down 2% from $4.9B the previous quarter. Its ten largest holdings account for 55% of the portfolio.

RTW Investments's Q1 2023 filing shows 7 new, 20 increased, 15 reduced and 24 closed positions. Its largest new stake was Bruker: 1,187,342 shares worth $93.6M. The largest sale was Thermo Fisher Scientific, an estimated $81.8M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

  • RTW Investments's largest Q1 2023 buy was Bruker: 1,187,342 shares worth $93.6M.
  • RTW Investments added most to Acadia Pharmaceuticals in Q1 2023, an estimated $87.1M increase.
  • RTW Investments's biggest Q1 2023 reduction was Thermo Fisher Scientific, cutting an estimated $81.8M.
  • RTW Investments fully exited Globus Medical in Q1 2023, selling an estimated $55.5M.
  • RTW Investments's ten largest holdings make up 55% of its $4.8B portfolio in Q1 2023.
  • RTW Investments opened 7 new positions and closed 24 in Q1 2023.
  • RTW Investments's portfolio value fell 2% quarter-over-quarter to $4.8B.

Based on RTW Investments's 13F filing for Q1 2023, filed 15 May 2023.