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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+23.77%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.34B
AUM Growth
+$467M
Cap. Flow
-$99.7M
Cap. Flow %
-2.3%
Top 10 Hldgs %
48.91%
Holding
111
New
4
Increased
17
Reduced
21
Closed
25

Top Buys

Rank Stock Value
1
RARE icon
Ultragenyx Pharmaceutical
RARE
+$50.7M
2
ISEE
IVERIC bio, Inc. Common Stock
ISEE
+$47.6M
3
PTCT icon
PTC Therapeutics
PTCT
+$28.2M
4
IMCR icon
Immunocore
IMCR
+$21.7M
5
AXSM icon
Axsome Therapeutics
AXSM
+$13.2M

Top Sells

Rank Stock Value
1
TNDM icon
Tandem Diabetes Care
TNDM
+$32.9M
2
QTRX icon
Quanterix
QTRX
+$29.5M
3
VERU icon
Veru
VERU
+$25.1M
4
GMED icon
Globus Medical
GMED
+$22.5M
5
AXNX
Axonics, Inc. Common Stock
AXNX
+$20.3M

Sector Composition

Rank Sector Weight
1 Healthcare 99.21%
2 Financials 0.67%
3 Industrials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
JNJ icon
76
Johnson & Johnson
JNJ
$625B
$2.96M 0.07%
18,127
– –
XGN icon
77
Exagen
XGN
$166M
$2.84M 0.07%
1,048,662
+23,660
+2% +$132K
ROIV icon
78
Roivant Sciences
ROIV
$26.2B
$2.58M 0.06%
802,717
– –
LABP
79
DELISTED
Landos Biopharma, Inc. Common Stock
LABP
$2.58M 0.06%
397,572
-30,000
-7% -$260K
EPIX
80
DELISTED
ESSA Pharma
EPIX
$2.39M 0.06%
1,311,294
-1,325,898
-50% -$3.49M
NYXH
81
Nyxoah
NYXH
$147M
$2.17M 0.05%
344,911
– –
ASLN
82
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$1.81M 0.04%
75,400
-5,850
-7% -$151K
NAUT icon
83
Nautilus Biotechnolgy
NAUT
$115M
$1.27M 0.03%
600,000
-500,000
-45% -$1.26M
MIRO
84
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
$1.23M 0.03%
280,000
– –
RCOR.WS
85
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$28K ﹤0.01%
350,000
– –
MSACW
86
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
$1K ﹤0.01%
33,331
– –
AGEN
87
Agenus
AGEN
$290M
– –
-80,696
Closed -$3.07M
ALGN icon
88
Align Technology
ALGN
$12.3B
– –
-42,000
Closed -$9.94M
CDXS icon
89
Codexis
CDXS
$158M
– –
-920,448
Closed -$9.63M
CTKB icon
90
Cytek Biosciences
CTKB
$546M
– –
-916,838
Closed -$9.84M
CTMX icon
91
CytomX Therapeutics
CTMX
$754M
– –
-2,849,707
Closed -$5.21M
CYRX icon
92
CryoPort
CYRX
$762M
– –
-335,299
Closed -$10.4M
MGNX icon
93
MacroGenics
MGNX
$257M
– –
-3,975,554
Closed -$11.7M
MXCT icon
94
MaxCyte
MXCT
$126M
– –
-772,735
Closed -$3.65M
PRCT icon
95
Procept Biorobotics
PRCT
$1.17B
– –
-161,138
Closed -$5.27M
PYXS icon
96
Pyxis Oncology
PYXS
$236M
– –
-682,220
Closed -$1.62M
QTRX icon
97
Quanterix
QTRX
$190M
– –
-1,819,120
Closed -$29.5M
RCEL icon
98
Avita Medical
RCEL
$240M
– –
-106,667
Closed -$507K
RXST icon
99
RxSight
RXST
$260M
– –
-150,000
Closed -$2.11M
TWST icon
100
Twist Bioscience
TWST
$7.25B
– –
-270,000
Closed -$9.44M
1 2 3
4
5

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RTW Investments's Q3 2022 Portfolio in Review

As of Q3 2022, RTW Investments held 111 positions worth $4.34B, up 12% from $3.87B the previous quarter. Its ten largest holdings account for 49% of the portfolio.

RTW Investments's Q3 2022 filing shows 4 new, 17 increased, 21 reduced and 25 closed positions. Its largest new stake was IVERIC bio, Inc. Common Stock: 3,625,000 shares worth $65M. The largest sale was Tandem Diabetes Care, an estimated $32.9M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, up from 99% a quarter earlier, followed by Financials and Industrials.

  • RTW Investments's largest Q3 2022 buy was IVERIC bio, Inc. Common Stock: 3,625,000 shares worth $65M.
  • RTW Investments added most to Ultragenyx Pharmaceutical in Q3 2022, an estimated $50.7M increase.
  • RTW Investments's biggest Q3 2022 reduction was Tandem Diabetes Care, cutting an estimated $32.9M.
  • RTW Investments fully exited Quanterix in Q3 2022, selling an estimated $29.5M.
  • RTW Investments's ten largest holdings make up 49% of its $4.34B portfolio in Q3 2022.
  • RTW Investments opened 4 new positions and closed 25 in Q3 2022.
  • RTW Investments's portfolio value rose 12% quarter-over-quarter to $4.34B.

Based on RTW Investments's 13F filing for Q3 2022, filed 14 Nov 2022.