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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-17.44%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$3.87B
AUM Growth
-$961M
Cap. Flow
+$318M
Cap. Flow %
8.21%
Top 10 Hldgs %
45.33%
Holding
116
New
10
Increased
28
Reduced
12
Closed
9

Top Buys

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$78.8M
2
IMCR icon
Immunocore
IMCR
+$69.4M
3
TMO icon
Thermo Fisher Scientific
TMO
+$34.4M
4
ARGX icon
argenx
ARGX
+$34M
5
MASI
Masimo
MASI
+$29.9M

Top Sells

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$36.9M
2
AXNX
Axonics, Inc. Common Stock
AXNX
+$30.9M
3
LONA
LeonaBio Inc
LONA
+$25.7M
4
ITOS
iTeos Therapeutics
ITOS
+$15.7M
5
VCEL icon
Vericel Corp
VCEL
+$14.6M

Sector Composition

Rank Sector Weight
1 Healthcare 98.86%
2 Financials 0.75%
3 Industrials 0.27%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PRCT icon
76
Procept Biorobotics
PRCT
$1.17B
$5.27M 0.14%
161,138
– –
CTMX icon
77
CytomX Therapeutics
CTMX
$754M
$5.21M 0.13%
2,849,707
-2,929,993
-51% -$5.61M
ARYD
78
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
$4.91M 0.13%
500,000
– –
SMIHU
79
DELISTED
Summit Healthcare Acquisition Corp. Units
SMIHU
$4.88M 0.13%
500,000
– –
ARYE
80
DELISTED
ARYA Sciences Acquisition Corp V Class A Ordinary Shares
ARYE
$4.86M 0.13%
500,000
– –
FVAM
81
DELISTED
5:01 Acquisition Corp
FVAM
$3.88M 0.1%
392,000
– –
MXCT icon
82
MaxCyte
MXCT
$126M
$3.65M 0.09%
772,735
+573,168
+287% +$2.82M
PNT
83
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$3.34M 0.09%
490,000
– –
ROIV icon
84
Roivant Sciences
ROIV
$26.2B
$3.27M 0.08%
802,717
– –
JNJ icon
85
Johnson & Johnson
JNJ
$625B
$3.22M 0.08%
18,127
– –
NYXH
86
Nyxoah
NYXH
$147M
$3.17M 0.08%
344,911
– –
LABP
87
DELISTED
Landos Biopharma, Inc. Common Stock
LABP
$3.11M 0.08%
427,572
– –
AGEN
88
Agenus
AGEN
$290M
$3.07M 0.08%
80,696
-101,831
-56% -$3.7M
IMTX icon
89
Immatics
IMTX
$1.32B
$3.05M 0.08%
350,000
– –
AKYA
90
DELISTED
Akoya BioSciences
AKYA
$3M 0.08%
233,557
+155,881
+201% +$1.62M
NAUT icon
91
Nautilus Biotechnolgy
NAUT
$115M
$2.96M 0.08%
1,100,000
– –
MSAC
92
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$2.93M 0.08%
300,000
– –
CTIC
93
DELISTED
CTI BioPharma Corp. (DE) Common Stock
CTIC
$2.82M 0.07%
+471,630
New +$2.41M
MLTX icon
94
MoonLake Immunotherapeutics
MLTX
$1.55B
$2.63M 0.07%
+500,000
New +$3.14M
RXST icon
95
RxSight
RXST
$260M
$2.11M 0.05%
150,000
– –
GTH
96
DELISTED
Genetron Holdings Limited ADS
GTH
$2.04M 0.05%
399,654
– –
PYXS icon
97
Pyxis Oncology
PYXS
$236M
$1.62M 0.04%
682,220
-1,438,540
-68% -$3.83M
ASLN
98
DELISTED
ASLAN Pharmaceuticals Limited American Depositary Shares
ASLN
$1.61M 0.04%
81,250
– –
MIRO
99
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
$1.12M 0.03%
280,000
– –
APEN
100
DELISTED
Apollo Endosurgery, Inc.
APEN
$942K 0.02%
258,064
– –
1 2 3
4
5

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RTW Investments's Q2 2022 Portfolio in Review

As of Q2 2022, RTW Investments held 116 positions worth $3.87B, down 20% from $4.83B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $318M of net new capital in Q2 2022, opening 10 new positions and adding to 28 existing holdings. Its largest new stake was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.

By sector, the portfolio is most concentrated in Healthcare at 99% of assets, down from 99% a quarter earlier, followed by Financials and Industrials.

On the sell side, the largest reduction was Globus Medical, an estimated $36.9M trimmed.

  • RTW Investments's largest Q2 2022 buy was Acadia Pharmaceuticals: 4,224,109 shares worth $59.5M.
  • RTW Investments added most to Immunocore in Q2 2022, an estimated $69.4M increase.
  • RTW Investments's biggest Q2 2022 reduction was Globus Medical, cutting an estimated $36.9M.
  • RTW Investments fully exited LeonaBio Inc in Q2 2022, selling an estimated $25.7M.
  • RTW Investments's ten largest holdings make up 45% of its $3.87B portfolio in Q2 2022.
  • RTW Investments opened 10 new positions and closed 9 in Q2 2022.
  • RTW Investments's portfolio value fell 20% quarter-over-quarter to $3.87B.

Based on RTW Investments's 13F filing for Q2 2022, filed 15 Aug 2022.