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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+10.81%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.15B
AUM Growth
+$599M
Cap. Flow
+$538M
Cap. Flow %
12.94%
Top 10 Hldgs %
45.29%
Holding
99
New
22
Increased
37
Reduced
6
Closed
9

Top Buys

Rank Stock Value
1
ILMN icon
Illumina
ILMN
+$62M
2
IMVT icon
Immunovant
IMVT
+$53.9M
3
CYTK icon
Cytokinetics
CYTK
+$46.8M
4
LONA
LeonaBio Inc
LONA
+$44.6M
5
GH icon
Guardant Health
GH
+$42.9M

Top Sells

Rank Stock Value
1
WVE icon
Wave Life Sciences
WVE
+$24.9M
2
QTTB icon
Q32 Bio
QTTB
+$22.8M
3
STAA icon
STAAR Surgical
STAA
+$19M
4
NEO icon
NeoGenomics
NEO
+$13.8M
5
RPTX
Repare Therapeutics
RPTX
+$6.98M

Sector Composition

Rank Sector Weight
1 Healthcare 92.6%
2 Materials 0.36%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CLSD
76
DELISTED
Clearside Biomedical
CLSD
$6.08M 0.15%
263,168
+1,993
+0.8% +$51.5K
QURE icon
77
uniQure
QURE
$3.22B
$5.84M 0.14%
158,479
+1,197
+0.8% +$49K
EQ icon
78
Equillium
EQ
$133M
$5.8M 0.14%
+1,004,784
New +$8.14M
PSNL icon
79
Personalis
PSNL
$1.51B
$5.53M 0.13%
255,000
– –
ARYBU
80
DELISTED
ARYA Sciences Acquisition Corp II Unit
ARYBU
$5.5M 0.13%
500,000
– –
NAUT icon
81
Nautilus Biotechnolgy
NAUT
$115M
$5.41M 0.13%
+500,000
New +$5.33M
PROF
82
Profound Medical
PROF
$269M
$4.31M 0.1%
244,193
+70,000
+40% +$1.11M
PHGE icon
83
BiomX
PHGE
$1.85M
$3.8M 0.09%
3,158
– –
IMTX icon
84
Immatics
IMTX
$1.32B
$3.71M 0.09%
+350,000
New +$3.69M
PANA.U
85
DELISTED
Panacea Acquisition Corp. Units, each consisting of one share of Class A common stock and one-third
PANA.U
$3.6M 0.09%
+300,000
New +$3.45M
CHAQ.U
86
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
$3.59M 0.09%
350,000
– –
BIOR
87
DELISTED
Biora Therapeutics, Inc. Common Stock
BIOR
$2.48M 0.06%
1,100
– –
TWST icon
88
Twist Bioscience
TWST
$7.25B
$1.4M 0.03%
18,473
– –
BNR
89
Burning Rock Biotech
BNR
$92.9M
$752K 0.02%
3,000
– –
PHGE.WS
90
DELISTED
BiomX Inc. Warrants to purchase one-half of a share of Common Stock
PHGE.WS
$426K 0.01%
600,000
– –
ARVN icon
91
Arvinas
ARVN
$572M
– –
-174,118
Closed -$5.84M
FLGT icon
92
Fulgent Genetics
FLGT
$527M
– –
-75,000
Closed -$1.2M
NEO icon
93
NeoGenomics
NEO
$2.13B
– –
-445,000
Closed -$13.8M
RPTX
94
DELISTED
Repare Therapeutics
RPTX
– –
-225,000
Closed -$6.98M
STAA icon
95
STAAR Surgical
STAA
$1.21B
– –
-308,904
Closed -$19M
WVE icon
96
Wave Life Sciences
WVE
$1.2B
– –
-2,390,496
Closed -$24.9M
NARI
97
DELISTED
Inari Medical, Inc. Common Stock
NARI
– –
-44,860
Closed -$2.17M
MOTS
98
DELISTED
Motus GI Holdings, Inc. Common Stock
MOTS
– –
-2,585
Closed -$1.02M
VRAY
99
DELISTED
ViewRay, Inc.
VRAY
– –
-150,000
Closed -$336K
1 2 3
4

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RTW Investments's Q3 2020 Portfolio in Review

As of Q3 2020, RTW Investments held 99 positions worth $4.15B, up 17% from $3.55B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments deployed $538M of net new capital in Q3 2020, opening 22 new positions and adding to 37 existing holdings. Its largest new stake was Illumina: 179,900 shares worth $54.1M.

By sector, the portfolio is most concentrated in Healthcare at 93% of assets, up from 91% a quarter earlier, followed by Materials.

On the sell side, the largest reduction was Q32 Bio, an estimated $22.8M trimmed.

  • RTW Investments's largest Q3 2020 buy was Illumina: 179,900 shares worth $54.1M.
  • RTW Investments added most to Immunovant in Q3 2020, an estimated $53.9M increase.
  • RTW Investments's biggest Q3 2020 reduction was Q32 Bio, cutting an estimated $22.8M.
  • RTW Investments fully exited Wave Life Sciences in Q3 2020, selling an estimated $24.9M.
  • RTW Investments's ten largest holdings make up 45% of its $4.15B portfolio in Q3 2020.
  • RTW Investments opened 22 new positions and closed 9 in Q3 2020.
  • RTW Investments's portfolio value rose 17% quarter-over-quarter to $4.15B.

Based on RTW Investments's 13F filing for Q3 2020, filed 16 Nov 2020.