RI

RTW Investments Portfolio holdings

AUM $7.02B
This Quarter Return
+7.31%
1 Year Return
+28.16%
3 Year Return
+245.48%
5 Year Return
+425.65%
10 Year Return
+5,642.23%
AUM
$6.91B
AUM Growth
+$6.91B
Cap. Flow
+$117M
Cap. Flow %
1.69%
Top 10 Hldgs %
46.12%
Holding
78
New
10
Increased
15
Reduced
10
Closed
10

Top Buys

1
GERN icon
Geron
GERN
$200M
2
SYK icon
Stryker
SYK
$143M
3
ORKA
Oruka Therapeutics, Inc. Common Stock
ORKA
$42.5M
4
MDGL icon
Madrigal Pharmaceuticals
MDGL
$16.5M
5
BIOA
BioAge Labs, Inc. Common Stock
BIOA
$16.4M

Top Sells

1
ISRG icon
Intuitive Surgical
ISRG
$90.1M
2
RARE icon
Ultragenyx Pharmaceutical
RARE
$71.8M
3
AXSM icon
Axsome Therapeutics
AXSM
$40M
4
VCEL icon
Vericel Corp
VCEL
$36.8M
5
FULC icon
Fulcrum Therapeutics
FULC
$36.2M

Sector Composition

1 Healthcare 99.89%
2 Financials 0.11%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
XNCR icon
51
Xencor
XNCR
$594M
$11.6M 0.17%
+575,000
New +$11.6M
TXG icon
52
10x Genomics
TXG
$1.66B
$11.4M 0.16%
502,856
– –
IMUX icon
53
Immunic
IMUX
$79.4M
$7.54M 0.11%
4,567,717
– –
PCSC
54
Perceptive Capital Solutions Corp Class A Ordinary Shares
PCSC
$117M
$7.43M 0.11%
742,500
– –
WVE icon
55
Wave Life Sciences
WVE
$1.27B
$7.38M 0.11%
+900,000
New +$7.38M
IDYA icon
56
IDEAYA Biosciences
IDYA
$2.26B
$6.34M 0.09%
+200,000
New +$6.34M
GPCR icon
57
Structure Therapeutics
GPCR
$1.14B
$5.49M 0.08%
125,000
– –
MIST icon
58
Milestone Pharmaceuticals
MIST
$151M
$4.95M 0.07%
3,256,102
– –
SLRN
59
DELISTED
ACELYRIN
SLRN
$4.82M 0.07%
978,310
– –
XGN icon
60
Exagen
XGN
$213M
$4.67M 0.07%
1,511,866
– –
RGNX icon
61
Regenxbio
RGNX
$498M
$3.67M 0.05%
350,000
– –
ARTV
62
Artiva Biotherapeutics, Inc. Common Stock
ARTV
$77.5M
$2.3M 0.03%
+148,844
New +$2.3M
ALUR icon
63
Allurion Technologies
ALUR
$16.5M
$2.27M 0.03%
147,902
– –
SABS icon
64
SAB Biotherapeutics
SABS
$21.6M
$1.72M 0.02%
635,276
-131,670
-17% -$356K
CNTA
65
Centessa Pharmaceuticals
CNTA
$2.13B
$800K 0.01%
+50,000
New +$800K
ADGM
66
Adagio Medical Holdings, Inc Common Stock
ADGM
$25.1M
$540K 0.01%
+209,361
New +$540K
QURE icon
67
uniQure
QURE
$954M
$49.3K ﹤0.01%
+10,000
New +$49.3K
RCKTW icon
68
Rocket Pharmaceuticals, Inc. Warrant
RCKTW
$4.17M
$22.6K ﹤0.01%
350,000
– –
SGMT icon
69
Sagimet Biosciences
SGMT
$239M
– –
-500,000
Closed -$1.71M
ACET icon
70
Adicet Bio
ACET
$60.8M
– –
-1,053,688
Closed -$1.27M
CTMX icon
71
CytomX Therapeutics
CTMX
$350M
– –
-1,200,002
Closed -$1.46M
FULC icon
72
Fulcrum Therapeutics
FULC
$353M
– –
-5,845,956
Closed -$36.2M
ISRG icon
73
Intuitive Surgical
ISRG
$158B
– –
-202,456
Closed -$90.1M
VCEL icon
74
Vericel Corp
VCEL
$1.69B
– –
-801,397
Closed -$36.8M
VRDN icon
75
Viridian Therapeutics
VRDN
$1.59B
– –
-605,816
Closed -$7.88M
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