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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+5.65%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$4.8B
AUM Growth
-$96.5M
Cap. Flow
+$4.8M
Cap. Flow %
0.1%
Top 10 Hldgs %
55.46%
Holding
84
New
7
Increased
20
Reduced
15
Closed
24

Top Buys

Rank Stock Value
1
ACAD icon
Acadia Pharmaceuticals
ACAD
+$87.1M
2
BRKR icon
Bruker
BRKR
+$85.7M
3
PTCT icon
PTC Therapeutics
PTCT
+$67.6M
4
AXSM icon
Axsome Therapeutics
AXSM
+$52.6M
5
OBIO icon
Orchestra BioMed
OBIO
+$47.7M

Top Sells

Rank Stock Value
1
TMO icon
Thermo Fisher Scientific
TMO
+$81.8M
2
GMED icon
Globus Medical
GMED
+$55.5M
3
RGNX icon
Regenxbio
RGNX
+$41.9M
4
ILMN icon
Illumina
ILMN
+$39.6M
5
BCYC
Bicycle Therapeutics
BCYC
+$37.3M

Sector Composition

Rank Sector Weight
1 Healthcare 99.97%
2 Financials 0.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
RLMD icon
51
Relmada Therapeutics
RLMD
$527M
$4.82M 0.1%
2,131,835
+64,011
+3% +$221K
JSPR icon
52
Jasper Therapeutics
JSPR
$23.6M
$4.22M 0.09%
+232,981
New +$4.31M
XGN icon
53
Exagen
XGN
$166M
$3.38M 0.07%
1,391,184
+26,848
+2% +$69.4K
AKYA
54
DELISTED
Akoya BioSciences
AKYA
$2.69M 0.06%
328,422
-155,393
-32% -$1.62M
THRD
55
DELISTED
Third Harmonic Bio
THRD
$2.2M 0.05%
534,687
-75,000
-12% -$318K
ARYD
56
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
$1.32M 0.03%
127,970
-372,030
-74% -$3.79M
MIRO
57
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
$748K 0.02%
445,222
+165,222
+59% +$429K
LSB
58
DELISTED
LakeShore Biopharma
LSB
$546K 0.01%
+34,109
New +$1.73M
SGHT icon
59
Sight Sciences
SGHT
$412M
$361K 0.01%
41,330
-623,993
-94% -$6.93M
RCKTW icon
60
Rocket Pharmaceuticals Warrant
RCKTW
$288K
$38.5K ﹤0.01%
+350,000
New +$67.5K
BCYC
61
Bicycle Therapeutics
BCYC
$292M
– –
-1,258,587
Closed -$37.3M
BWAY
62
Brainsway
BWAY
$622M
– –
-3,204,762
Closed -$3.96M
CCCC icon
63
C4 Therapeutics
CCCC
$412M
– –
-2,819,472
Closed -$16.6M
GLUE icon
64
Monte Rosa Therapeutics
GLUE
$1.35B
– –
-1,214,572
Closed -$9.24M
GMED icon
65
Globus Medical
GMED
$11.2B
– –
-747,685
Closed -$55.5M
JNJ icon
66
Johnson & Johnson
JNJ
$625B
– –
-18,127
Closed -$3.2M
LUNG icon
67
Pulmonx
LUNG
$87.6M
– –
-275,000
Closed -$2.32M
MASS icon
68
908 Devices
MASS
$364M
– –
-312,000
Closed -$2.38M
NAUT icon
69
Nautilus Biotechnolgy
NAUT
$115M
– –
-600,000
Closed -$1.08M
NYXH
70
Nyxoah
NYXH
$147M
– –
-269,993
Closed -$1.35M
RGNX icon
71
Regenxbio
RGNX
$708M
– –
-1,845,366
Closed -$41.9M
TELA icon
72
TELA Bio
TELA
$38.9M
– –
-390,364
Closed -$4.49M
TERN
73
DELISTED
Terns Pharmaceuticals
TERN
– –
-1,000,000
Closed -$10.2M
TNYA icon
74
Tenaya Therapeutics
TNYA
$163M
– –
-2,458,750
Closed -$4.94M
WHWK
75
Whitehawk Therapeutics
WHWK
$271M
– –
-764,701
Closed -$9.81M
1 2
3
4

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MF
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RTW Investments's Q1 2023 Portfolio in Review

As of Q1 2023, RTW Investments held 84 positions worth $4.8B, down 2% from $4.9B the previous quarter. Its ten largest holdings account for 55% of the portfolio.

RTW Investments's Q1 2023 filing shows 7 new, 20 increased, 15 reduced and 24 closed positions. Its largest new stake was Bruker: 1,187,342 shares worth $93.6M. The largest sale was Thermo Fisher Scientific, an estimated $81.8M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

  • RTW Investments's largest Q1 2023 buy was Bruker: 1,187,342 shares worth $93.6M.
  • RTW Investments added most to Acadia Pharmaceuticals in Q1 2023, an estimated $87.1M increase.
  • RTW Investments's biggest Q1 2023 reduction was Thermo Fisher Scientific, cutting an estimated $81.8M.
  • RTW Investments fully exited Globus Medical in Q1 2023, selling an estimated $55.5M.
  • RTW Investments's ten largest holdings make up 55% of its $4.8B portfolio in Q1 2023.
  • RTW Investments opened 7 new positions and closed 24 in Q1 2023.
  • RTW Investments's portfolio value fell 2% quarter-over-quarter to $4.8B.

Based on RTW Investments's 13F filing for Q1 2023, filed 15 May 2023.